Evidence map›Paper›PMID 28108112›Full record

ArticleTrends in molecular medicine2017

The Olfactory Neural Epithelium As a Tool in Neuroscience.

Joëlle Lavoie, Patricia Gassó Astorga, Hadar Segal-Gavish, YeeWen Candace Wu, Youjin Chung, Nicola G Cascella, Akira Sawa, Koko Ishizuka

Abstract read
In one paragraph

Article in Trends in molecular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joëlle LavoieDepartment of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Patricia Gassó AstorgaDepartment of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Current address: Faculty of Medicine, University of Barcelona, Barcelona, Spain.
Hadar Segal-GavishDepartment of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Current address: Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
YeeWen Candace WuDepartment of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Youjin ChungDepartment of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Current address: Jacobs School of Medicine and Biomedical Sciences, SUNY Buffalo, Buffalo, NY, USA.
Nicola G CascellaSheppard Pratt Hospital, Baltimore, MD, USA.
Akira SawaDepartment of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: asawa1@jhmi.edu.
Koko IshizukaDepartment of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: kishizu2@jhmi.edu.

Funding

Project 3P50MH094268 · NIMH · JOHNS HOPKINS UNIVERSITY · PI LEEK, JEFFREY T. · 2011 to 2020
$19.9M
Research Center for Molecular Pathogenesis of SchizophreniaP20MH084018 · NIMH · JOHNS HOPKINS UNIVERSITY · PI GALLAGHER, MICHAELA · 2008 to 2010
$3.3M
DISC1-dependent defects in neural fate, corticogenesis and cognition in psychosisR01MH105660 · NIMH · JOHNS HOPKINS UNIVERSITY · PI ISHIZUKA, KOKO, SAWA, AKIRA · 2014 to 2018
$2.8M
Oxidative stress and schizophrenia: combination of cell biology and brain imagingR01MH092443 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SAWA, AKIRA · 2011 to 2015
$1.8M
CIHRNIMH NIH HHS P20 MH084018NIMH NIH HHS P50 MH094268NIMH NIH HHS R01 MH092443NIMH NIH HHS R01 MH105660
6 · The paper itself

Abstract

Capturing both dynamic changes (state) and persistent signatures (trait) directly associated with disease at the molecular level is crucial in modern medicine. The olfactory neural epithelium, easily accessible in clinical settings, is a promising surrogate model in translational brain medicine, complementing the limitations in current engineered cell models.

Indexed as

AnimalsCell Culture TechniquesCentral Nervous System DiseasesDrug DiscoveryHumansLaser Capture MicrodissectionNeurosciencesOlfactory MucosaOlfactory Receptor Neurons

Identifiers

PMID28108112
PMCPMC5399677

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.