ArticleSubstance abuse treatment, prevention, and policy2017
Implementation of methadone therapy for opioid use disorder in Russia - a modeled cost-effectiveness analysis.
Article in Substance abuse treatment, prevention, and policy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Economic Evaluations of Pharmacologic Treatment for Opioid Use Disorder: A Systematic Literature Review.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2021Pooled it
- Comparative costs and potential affordability of a multifaceted intervention to improve treatment outcomes among people with HIV who inject drugs in Russia: economic evaluation of the LINC-II randomized controlled trial.Journal of the International AIDS Society · 2024Trial
- Stigma and other correlates of sharing injection equipment among people with HIV in St. Petersburg, Russia.Global public health · 2024Article
- Adjunctive Management of Opioid Withdrawal with the Nonopioid Medication Cannabidiol.Cannabis and cannabinoid research · 2022Review
- Molecular epidemiology of HIV-1 in Oryol Oblast, Russia.Virus evolution · 2022Article
- Linking HIV-positive people in addiction care to HIV services in St. Petersburg, Russia - Mixed-methods implementation study of strengths-based case management.Global public health · 2021Article
- Information Needs of Addicted Individuals: A Qualitative Case Study.Addiction & health · 2021Article
- Healthcare delivery for HIV-positive people with tuberculosis in Europe.HIV medicine · 2021Article
- An Economic Analysis of the Implementation of Team-based Collaborative Care in Outpatient General Mental Health Clinics.Medical care · 2020Article
- Opioid epidemic and liver disease.JHEP reports : innovation in hepatology · 2019Review
- Evolving HIV epidemics: the urgent need to refocus on populations with risk.Current opinion in HIV and AIDS · 2019Review
- Article
- National Institute on Drug Abuse International Program: improving opioid use disorder treatment through international research training.Current opinion in psychiatry · 2018Review
- Role of substance use in HIV care cascade outcomes among people who inject drugs in Russia.Addiction science & clinical practice · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundOpioid agonist therapy using methadone, an effective treatment of opioid use disorders (OUD) for people who inject drugs (PWID), is recommended by the World Health Organization as essential to curtail the growing HIV epidemic. Yet, despite increasing prevalence of OUD and HIV, methadone therapy has not yet been implemented in Russia. The aim of this modeling study was to estimate the cost-effectiveness of methadone therapy for Russian adults with a diagnosed OUD. METHODS/
designWe modeled the projected program implementation costs and estimated disability-adjusted life years (DALYs) averted over a 10-year period, associated with the provision of methadone therapy for a hypothetical, unreplenished cohort of Russian adults with an OUD (n = 249,000), in comparison to the current therapies at existing addiction treatment facilities. Our model compared four distinct scenarios of treatment coverage in the cohort ranging from 3.1 to 55%.
resultsProviding methadone therapy to as few as 3.1% of adults with an OUD amounted to an estimated almost 50,000 DALYs averted over 10 years at a cost of just over USD 17 million. Further expanding service coverage to 55% resulted in an estimated almost 900,000 DALYs averted, at a cost of about USD 308 million.
conclusionOur study indicated that implementing opioid agonist therapy with methadone to treat OUD at existing facilities in Russia is highly cost-effective.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.