Evidence map›Paper›PMID 28107772›Full record

Trial reportAddiction (Abingdon, England)2017

A preliminary randomized controlled trial of contingency management for alcohol use reduction using a transdermal alcohol sensor.

Nancy P Barnett, Mark A Celio, Jennifer W Tidey, James G Murphy, Suzanne M Colby, Robert M Swift

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Addiction (Abingdon, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 4 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 4 syntheses or guidelines pooled it, 115 citations in OpenAlex.

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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nancy P BarnettCenter for Alcohol and Addiction Studies, Brown University, Providence, RI, USA.
Mark A CelioCenter for Alcohol and Addiction Studies, Brown University, Providence, RI, USA.
Jennifer W TideyCenter for Alcohol and Addiction Studies, Brown University, Providence, RI, USA.
James G MurphyDepartment of Psychology, University of Memphis, Memphis, TN, USA.
Suzanne M ColbyCenter for Alcohol and Addiction Studies, Brown University, Providence, RI, USA.
Robert M SwiftCenter for Alcohol and Addiction Studies, Brown University, Providence, RI, USA.
Brown University · USUniversity of Memphis · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
ALCOHOL INTERVENTION/TREATMENT OUTCOME RESEARCH TRAININGT32AA007459 · NIAAA · BROWN UNIVERSITY · PI ROBERT MIRANDA, PETER M. MONTI · 1986 to 2026
$13.3M
Effects of Acute Alcohol on Sex-Specific Delay Discounting and Subsequent Sexual Decision Making among MSMK08AA024056 · NIAAA · BROWN UNIVERSITY · PI CELIO, MARK ANTHONY · 2016 to 2018
$571k
Contingency Management for Alcohol Abuse Using Transdermal Alcohol DetectionR21AA015980 · NIAAA · BROWN UNIVERSITY · PI BARNETT, NANCY P · 2008 to 2009
$422k
A Multi-Component Data Processing Program for Transdermal Alcohol SensorsR21AA020943 · NIAAA · BROWN UNIVERSITY · PI BARNETT, NANCY P · 2012 to 2013
$412k
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS K08 AA024056NIAAA NIH HHS R21 AA015980NIAAA NIH HHS R21 AA020943NIAAA NIH HHS T32 AA007459
6 · The paper itself

Abstract

aimsWe tested the efficacy of daily contingent reinforcement for reducing alcohol use compared with (yoked) non-contingent reinforcement (NR) using a transdermal alcohol sensor to detect alcohol use.

designPilot randomized controlled design with 1 baseline week, 3 intervention weeks and 1-month follow-up.

settingNew England, USA.

participantsHeavy drinking adults (46.7% female) not seeking treatment were randomized to (1) an escalating schedule of cash reinforcement (CR; n = 15) for days on which alcohol was neither reported nor detected or (2) yoked NR (n = 15). INTERVENTION AND COMPARATOR: Reinforcement for CR participants started at $5 and increased $2 every subsequent day on which alcohol was not detected or reported, to a maximum of $17. Participants received no reinforcement for days on which alcohol use was detected or reported, and the reinforcer value was re-set to $5 the day after a drinking day. NR participants were yoked to the daily reinforcer value of an individual in the CR condition, in order of enrollment. Paired participants in CR and NR therefore received the same amount of money, but the amount for the NR participant was not behavior-related. MEASUREMENTS: The primary outcome was percentage of days without sensor-detected drinking. Secondary outcomes were number of consecutive days with no detected drinking, peak transdermal alcohol concentration (TAC), self-reported drinks per week and drinking below NIH low-risk guidelines.

findingsControlling for baseline, CR had a higher percentage of days with no drinking detected (54.3%) than NR (31.2%) during intervention weeks [P = 0.05, Cohen's d = 0.74; 95% confidence interval (CI) = 0.007-1.47]. The longest period of consecutive days with no drinking detected was 8.0 for CR versus 2.9 for NR (P = 0.03, d = 0.85; 95% CI = 0.08-1.61). Peak TAC during intervention showed a non-significant group difference (P = 0.20; d = 0.48; 95% CI = 0.00-1.18); a similar result was found for drinks per week (P = 0.12; d = 0.59; 95% CI = 0.00-1.30). Four times more participants in CR drank below NIH low-risk drinking guidelines during intervention than did participants in NR: 31.1 versus 7.1% (P = 0.07; d = 0.71; 95% CI = -0.04 to 1.46). At 1-month follow-up, the highest number of consecutive days without drinking (self-report) did not differ significantly between conditions (P = 0.26), but showed a medium effect size (d = 0.44; 95% CI = -0.32 to 1.18).

conclusionsCash incentives linked to a transdermal alcohol sensor can reduce heavy alcohol consumption while the incentives are in operation.

Indexed as

Reinforcement, PsychologyAdultAlcoholismEthanolFemaleFollow-Up StudiesHumansMaleMiddle AgedMonitoring, AmbulatoryMotivationNew EnglandPilot ProjectsSkinTreatment OutcomeYoung AdultEthanolAlcoholbiosensorcontingency managementmonitoringreinforcementtransdermal

Identifiers

PMID28107772
PMCPMC5407929
OpenAlexW2581389537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.