Evidence map›Paper›PMID 28107771›Full record

ArticleActa obstetricia et gynecologica Scandinavica2017

A prospective study of maternal, fetal and neonatal outcomes in the setting of cesarean section in low- and middle-income countries.

Margo S Harrison, Omrana Pasha, Sarah Saleem, Sumera Ali, Elwyn Chomba, Waldemar A Carlo, Ana L Garces, Nancy F Krebs, K Michael Hambidge, Shivaprasad S Goudar and 16 more

Open access · hybridAbstract read
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
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  4. Delivery outcomes in women with previous caesarean delivery at Zithulele Hospital - A rural district hospital managed by generalist doctors.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 17 institutions in 8 countries.

Margo S HarrisonDepartment of Obstetrics and Gynecology, Columbia University, New York, NY, USA.
Omrana PashaDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.ORCID http://orcid.org/0000-0003-2000-4001
Sarah SaleemDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.ORCID http://orcid.org/0000-0002-6797-8631
Sumera AliDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Elwyn ChombaUniversity Teaching Hospital, University of Zambia, Lusaka, Zambia.
Waldemar A CarloDivision of Neonatology, University of Alabama, Birmingham, AL, USA.
Ana L GarcesPlanning Unit, Institute of Nutrition of Central America and Panama (INCAP), Guatemala City, Guatemala.
Nancy F KrebsSchool of Medicine, University of Colorado, Denver, CO, USA.
K Michael HambidgeSchool of Medicine, University of Colorado, Denver, CO, USA.
Shivaprasad S GoudarJawaharlal Nehru Medical College, KLE University, Belgaum, India.
Bhala KodkanyJawaharlal Nehru Medical College, KLE University, Belgaum, India.
Sangappa DhadedJawaharlal Nehru Medical College, KLE University, Belgaum, India.
Richard J DermanDepartment of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA, USA.
Archana PatelLata Medical Research Foundation, Nagpur, India.
Patricia L HibberdSchool of Public Health, Boston University, Boston, MA, USA.
Fabian EsamaiSchool of Medicine, Moi University, Eldoret, Kenya.
Edward A LiechtySchool of Medicine, Indiana University, Indianapolis, IN, USA.
Janet L MooreRTI International, Durham, NC, USA.
Dennis WallaceRTI International, Durham, NC, USA.
Elizabeth M McclureRTI International, Durham, NC, USA.ORCID http://orcid.org/0000-0001-8659-5444
Menachem MiodovnikPregnancy and Perinatology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.
Marion Koso-ThomasPregnancy and Perinatology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.
Jose BelizanInstitute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.
Antoinette K TshefuKinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.
Melissa BausermanDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Robert L GoldenbergDepartment of Obstetrics and Gynecology, Columbia University, New York, NY, USA.
Aga Khan University · PKJawaharlal Nehru Medical College · INRTI International · USColumbia University · USNational Institutes of Health · USUniversity of Colorado Denver · USBoston University · USIndiana University Indianapolis · USInstitute of Nutrition of Central America and Panama · GTInstituto de Efectividad Clínica y Sanitaria · ARLata Medical Research Foundation · INMinistry of Public Health · CDMoi University · KEThomas Jefferson University · USUniversity of Alabama at Birmingham · USUniversity of North Carolina at Chapel Hill · USUniversity Teaching Hospital · ZM

Funding

Zika in Pregnancy Supplemental Funding requestU01HD040636 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI MCCLURE, ELIZABETH M · 2001 to 2017
$37.5M
Global Network for Women's and Children's Health Research Data Coordinating CenterU24HD092094 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI Elizabeth M McClure · 2017 to 2026
$17.8M
UAB/AKU Global Network Research UnitU01HD040607 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOLDENBERG, ROBERT L · 2001 to 2012
$8.5M
Complementary feeding: a Global Network cluster randomized controlled trialU01HD040657 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HAMBIDGE, K MICHAEL · 2001 to 2012
$8.1M
UMKC-JNMC Global Network for Women's and Children's Health Research UnitU01HD042372 · NICHD · UNIVERSITY OF MISSOURI KANSAS CITY · PI DERMAN, RICHARD J · 2001 to 2012
$6.9M
Neonatal Resuscitation in Developing CountriesU01HD043464 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARLO FONT, WALDEMAR A. · 2003 to 2012
$6.6M
Evidence-Based Global Health Interventions for Mothers and Children, ArgentinaU01HD040477 · NICHD · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI BUEKENS, PIERRE · 2001 to 2013
$5.6M
Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research UnitUG1HD078439 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Patricia L Hibberd · 2018 to 2026
$5.5M
TJU-JNMC Global Network for Women's & Children's Health Research UnitUG1HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI RICHARD J DERMAN · 2018 to 2026
$5.5M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
Safe Pregnancy by Infectious Disease Control in KinshasaU01HD043475 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOSE, CARL · 2003 to 2008
$5.2M
The Global Network and Preconception Maternal NutritionU10HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HAMBIDGE, K MICHAEL, KREBS, NANCY F · 2013 to 2017
$5.1M
NCCIH NIH HHS K24 AT003683NICHD NIH HHS U01 HD040477NICHD NIH HHS U01 HD040574NICHD NIH HHS U01 HD040607NICHD NIH HHS U01 HD040636NICHD NIH HHS U01 HD040657NICHD NIH HHS U01 HD042372NICHD NIH HHS U01 HD043464NICHD NIH HHS U01 HD043475NICHD NIH HHS U01 HD058322NICHD NIH HHS U10 HD076457NICHD NIH HHS U10 HD076474NICHD NIH HHS U10 HD078437NICHD NIH HHS U10 HD078438NICHD NIH HHS U10 HD078439NICHD NIH HHS U24 HD092094NICHD NIH HHS UG1 HD076457NICHD NIH HHS UG1 HD076474NICHD NIH HHS UG1 HD078439
6 · The paper itself

Abstract

introductionCesarean section (CS) rates are increasing globally with an unclear effect on pregnancy outcomes. The study objective was to quantify maternal and perinatal morbidity and mortality associated with CS compared with vaginal delivery (VD) both within and across sites in low- and middle-income countries. MATERIAL AND

methodsA prospective population-based study including home and facility births in 337 153 women with a VD and 47 308 women with a CS from 2010 to 2015 was performed in Guatemala, India, Kenya, Pakistan, Zambia and Democratic Republic of Congo. Women were enrolled during pregnancy; delivery and 6-week follow-up data were collected.

resultsAcross all sites, CS rates increased from 8.6% to 15.2%, but remained low in African sites. Younger, nulliparous women were more likely to have a CS, as were women with higher education and those delivering an infant weighing 1500-2499 g. Across all sites, maternal and neonatal mortality was higher, and stillbirths were lower, in pregnancies delivered by CS. Antepartum and postpartum complications as well as obstetric interventions and treatments were more common among women who underwent CS. In stratified analyses, all outcomes were worse in women with a CS compared with VD in African compared to non-African sites.

conclusionsCS rates increased across all sites during the study period, but at more pronounced rates in the non-African sites. CS was associated with reduced postpartum hemorrhage and lower rates of stillbirths in the non-African sites. In the African sites, CS was associated with an increase in all adverse outcomes. Further studies are necessary to better understand the increase in adverse outcomes with CS in the African sites.

Indexed as

AdultCesarean SectionDeveloping CountriesFemaleHumansInfantInfant MortalityInfant, NewbornMaleMaternal Health ServicesMaternal MortalityObstetric Labor ComplicationsPregnancyPregnancy OutcomeProspective StudiesSocioeconomic FactorsCesarean sectionlow- and middle-income countriesmaternal morbiditymaternal mortalityneonatal morbidityneonatal mortality

Identifiers

PMID28107771
PMCPMC5665564
OpenAlexW2579317622

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.