Evidence map›Paper›PMID 28107221›Full record

ArticleAIDS (London, England)2017

Cash vs. food assistance to improve adherence to antiretroviral therapy among HIV-infected adults in Tanzania.

Sandra I McCoy, Prosper F Njau, Carolyn Fahey, Ntuli Kapologwe, Suneetha Kadiyala, Nicholas P Jewell, William H Dow, Nancy S Padian

Registry-linked trialAbstract read
In one paragraph

Article in AIDS (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01957917 (Comparing Food and Cash Assistance for HIV-Positive Men and Women on Antiretroviral Therapy in Tanzania), which is not on this map. Cited by 61 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01957917 nacompletednot on this map

Comparing Food and Cash Assistance for HIV-Positive Men and Women on Antiretroviral Therapy in Tanzania

TypeinterventionalSponsorUniversity of California, BerkeleyRan2013 to 2019Enrolled800ConditionsHIVArmsNAC (Nutritional Assessment and Counseling), Cash Transfer, Food Assistance
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sandra I McCoyaDivision of Epidemiology, University of California, Berkeley, California, USA bPrevention of Mother-to-Child HIV Transmission Programme, Ministry of Health, Community Development, Gender, Elderly, and Children, Dar es Salaam cRegional Medical Office, Ministry of Health, Community Development, Gender, Equity, and Children, Shinyanga, Tanzania dFaculty of Epidemiology and Population Health, Department of Population Health, London School of Hygiene & Tropical Medicine, London, UK eDivision of Biostatistics fDivision of Health Policy and Management, University of California, Berkeley, California, USA.
Prosper F Njau
Carolyn Fahey
Ntuli Kapologwe
Suneetha Kadiyala
Nicholas P Jewell
William H Dow
Nancy S Padian

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Global Health Fellows and Scholars Research TrainingR25TW009338 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI BARRY, MICHELE, KO, ALBERT ICKSANG · 2012 to 2016
$5.2M
Agricultural Livelihoods, Food Security, and Women's Risk of HIV InfectionK01MH094246 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI MCCOY, SANDRA I · 2011 to 2015
$1.0M
Berkeley Population CenterR24HD073964 · NICHD · UNIVERSITY OF CALIFORNIA BERKELEY · PI HOUT, MICHAEL · 2014 to 2017
$466k
Statistical Design and Analysis of Cluster Randomized Test-Negative Designs: Studies to Eliminate Dengue FeverR56AI134724 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI JEWELL, NICHOLAS P · 2018 to 2018
$187k
FIC NIH HHS D43 TW010540FIC NIH HHS R25 TW009338NIAID NIH HHS R56 AI134724NICHD NIH HHS R24 HD073964NIMH NIH HHS K01 MH094246PEPFAR
6 · The paper itself

Abstract

objectiveWe evaluated the effectiveness of short-term cash and food assistance to improve adherence to antiretroviral therapy (ART) and retention in care among people living with HIV in Tanzania.

methodsAt three clinics, 805 participants were randomized to three groups in a 3 : 3 : 1 ratio, stratified by site : nutrition assessment and counseling (NAC) and cash transfers (∼$11/month, n = 347), NAC and food baskets (n = 345), and NAC-only (comparison group, n = 113, clinicaltrials.gov NCT01957917). Eligible people living with HIV were at least 18 years, initiated ART 90 days or less prior, and food insecure. Cash or food was provided for 6 or less consecutive months, conditional on visit attendance. The primary outcome was medication possession ratio (MPR ≥ 95%) at 6 months. Secondary outcomes were appointment attendance and loss to follow-up (LTFU) at 6 and 12 months.

resultsThe primary intent-to-treat analysis included 800 participants. Achievement of MPR ≥ 95% at 6 months was higher in the NAC + cash group compared with NAC-only (85.0 vs. 63.4%), a 21.6 percentage point difference [95% confidence interval (CI): 9.8, 33.4, P < 0.01]. MPR ≥ 95% was also significantly higher in the NAC + food group vs. NAC-only (difference = 15.8, 95% CI: 3.8, 27.9, P < 0.01). When directly compared, MPR ≥ 95% was similar in the NAC + cash and NAC + food groups (difference = 5.7, 95% CI: -1.2, 12.7, P = 0.15). Compared with NAC-only, appointment attendance and LTFU were significantly higher in both the NAC + cash and NAC + food groups at 6 months. At 12 months, the effect of NAC + cash, but not NAC + food, on MPR ≥ 95% and retention was sustained.

conclusionShort-term conditional cash and food assistance improves ART possession and appointment attendance and reduces LTFU among food-insecure ART initiates in Tanzania.

Indexed as

Food AssistanceRemunerationAdultAnti-Retroviral AgentsHIV InfectionsHumansMedication AdherenceTanzaniaAnti-Retroviral Agents

Identifiers

PMID28107221
PMCPMC5342932

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.