ReviewCurrent opinion in pediatrics2017
Environment, susceptibility windows, development, and child health.
Review in Current opinion in pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed.
- Multi-Tree Model for Precision Environmental Health with Longitudinally Assessed Mixture Exposure.Journal of the Royal Statistical Society. Series C, Applied statistics · 2026Article
- Environmental hazards and the risk of development of idiopathic urethral strictures.Translational andrology and urology · 2026Article
- Integrating omics and artificial intelligence in pediatric environmental health: tools, challenges, and cohort-based insights.Pediatric research · 2026Review
- Implications of Endocrine-Disrupting Chemicals for Human Health and Effective Methods for Prevention and Reduction.Toxics · 2026Review
- Air Pollution Exposure and Birth Weight in the ECHO Cohort.JAMA network open · 2025Article
- Smooth and shape-constrained quantile distributed lag models.Biometrics · 2025Article
- Environmental public health research at the U.S. Environmental Protection Agency: A blueprint for exposure science in a connected world.Journal of exposure science & environmental epidemiology · 2025Review
- The Homeobox Transcription Factor CUX1 Coordinates Postnatal Epithelial Developmental Timing but Is Dispensable for Lung Organogenesis and Regeneration.American journal of respiratory cell and molecular biology · 2025Article
- Increasing temporal sensitivity of omics association studies with epigenome-wide distributed lag models.American journal of epidemiology · 2025Article
- Advancing translational exposomics: bridging genome, exposome and personalized medicine.Human genomics · 2025Review
- Per- and polyfluoroalkyl substances (PFAS): immunotoxicity at the primary sites of exposure.Critical reviews in toxicology · 2025Review
- Understanding prenatal household exposures to per- and polyfluorylalkyl substances using paired Biological and dust measurements with sociodemographic and housing variables.Environment international · 2024Article
- Associations between prenatal metal and metalloid mixtures in teeth and reductions in childhood lung function.The Science of the total environment · 2024Article
- Early-life exposure to tobacco, genetic susceptibility, and accelerated biological aging in adulthood.Science advances · 2024Article
- Toenail and serum levels as biomarkers of iron status in pre- and postmenopausal women: correlations and stability over eight-year follow-up.Scientific reports · 2024Article
- Heterogeneous Distributed Lag Models to Estimate Personalized Effects of Maternal Exposures to Air Pollution.Journal of the American Statistical Association · 2024Article
- Review
- Multiple exposure distributed lag models with variable selection.Biostatistics (Oxford, England) · 2023Article
- Early origins of health and disease risk: The case for investigating adverse exposures and biological aging in utero, across childhood, and into adolescence.Child development perspectives · 2023Article
- Associations of green and blue space exposure in pregnancy with epigenetic gestational age acceleration.Epigenetics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
purpose of reviewTo illustrate the role of the exposome in child health while highlighting unique aspects of this research pertinent to children, such as the time dependency of environmental exposures on fetal programming, as well as the time-dependent nature of child behavior, diet, and motor function, which alter the probability of exposure to different compounds. Future environmental health research will be more hypothesis generating but will also need to heed lessons learned from other 'omic' sciences. The NIH Child Health Environmental Analysis Resource (CHEAR) is a major step toward providing the infrastructure needed to study the exposome and child health. RECENT
findingsEnvironmental exposures have overlapping mechanisms such as endocrine disruption and oxidative stress, among others. The nature of the long-term health impact of an exposure is dependent not only on dose, but also on the timing of exposure. Advances in exposure science, toxicology, and biostatistics will create new opportunities to identify and better define windows of susceptibility to environmental exposures. SUMMARY: As exposure science matures, we will better understand the role of environment on health. Linking the exposome with genomics will unlock the root origins of multiple complex diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.