Evidence map›Paper›PMID 28106738›Full record

ArticleInternational journal of molecular sciences2017

6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice.

Chien-Kei Wei, Yi-Hong Tsai, Michal Korinek, Pei-Hsuan Hung, Mohamed El-Shazly, Yuan-Bin Cheng, Yang-Chang Wu, Tusty-Jiuan Hsieh, Fang-Rong Chang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 164 citations in OpenAlex.

  1. Pharmacological properties of ginger (Frontiers in pharmacology · 2025
    Pooled it
  2. Trial
  3. Drug design, development and therapy · 2022
    Trial
  4. Review
  5. Review
  6. Article
  7. Impact of Ginger on Gut Microbiota Composition and Function in aJournal of microbiology and biotechnology · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Chien-Kei WeiGraduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan. weichankai@yahoo.com.tw.
Yi-Hong TsaiGraduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan. lyph0719@hotmail.com.
Michal KorinekGraduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan. mickorinek@hotmail.com.
Pei-Hsuan HungGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan. vean1990@hotmail.com.
Mohamed El-ShazlyGraduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan. mohamed.elshazly@pharm.asu.edu.eg.
Yuan-Bin ChengGraduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan. jmb@kmu.edu.tw.
Yang-Chang WuGraduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan. yachwu@mail.cmu.edu.tw.
Tusty-Jiuan HsiehGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan. hsiehjun@kmu.edu.tw.
Fang-Rong ChangGraduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan. aaronfrc@kmu.edu.tw.
Kaohsiung Medical University · TWNational Sun Yat-sen University · TWAin Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anti-diabetic activity of ginger powder (

Indexed as

3T3-L1 CellsAdipocytesAMP-Activated Protein KinasesAnimalsBlood GlucoseCatecholsCell LineDiabetes Mellitus, Type 2Diet, High-FatGlucoseGlucose Tolerance TestGuaiacolHumansHyperglycemiaImmunoblottingKetones6-paradolAMP-Activated Protein KinasesBlood GlucoseCatecholsGlucoseGuaiacolKetonesLipidsshogaol3T3-L1 adipocytes6-paradolC2C12 myotubesdiabetes mellitushigh-fat diet-fed miceshogaols

Identifiers

PMID28106738
PMCPMC5297801
OpenAlexW2574668764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.