Evidence map›Paper›PMID 28106145›Full record

ArticleScientific reports2017

CD1

Jane C Edwards, Helen E Everett, Miriam Pedrera, Helen Mokhtar, Emanuele Marchi, Ferran Soldevila, Daryan A Kaveh, Philip J Hogarth, Helen L Johns, Javier Nunez-Garcia and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
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  6. Article
  7. Frontiers in immunology · 2022
    Article
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  11. Review
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jane C EdwardsVirology Department, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Helen E EverettVirology Department, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Miriam PedreraVirology Department, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Helen MokhtarVirology Department, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Emanuele MarchiNuffield Department of Medicine, University of Oxford, Oxford, OX1 3SY, UK.
Ferran SoldevilaVirology Department, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Daryan A KavehFlow Cytometry Facility, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Philip J HogarthFlow Cytometry Facility, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Helen L JohnsVirology Department, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Javier Nunez-GarciaEpidemiology Department, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Falko SteinbachVirology Department, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Helen R CrookeVirology Department, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Simon P GrahamVirology Department, Animal and Plant Health Agency, Addlestone, KT15 3NB, UK.
Animal and Plant Health Agency · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional dendritic cells (cDC) are professional antigen-presenting cells that induce immune activation or tolerance. Two functionally specialised populations, termed cDC1 and cDC2, have been described in humans, mice, ruminants and recently in pigs. Pigs are an important biomedical model species and a key source of animal protein; therefore further understanding of their immune system will help underpin the development of disease prevention strategies. To characterise cDC populations in porcine blood, DC were enriched from PBMC by CD14 depletion and CD172a enrichment then stained with lineage mAbs (Lin; CD3, CD8α, CD14 and CD21) and mAbs specific for CD172a, CD1 and CD4. Two distinct porcine cDC subpopulations were FACSorted CD1

Indexed as

AnimalsAntigens, CD1Antigens, SurfaceBlood CellsCytokinesDendritic CellsFlow CytometryGene Expression ProfilingSwineSwine DiseasesAntigens, CD1Antigens, SurfaceCytokines

Identifiers

PMID28106145
PMCPMC5247722
OpenAlexW2574289416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.