Evidence map›Paper›PMID 28106111›Full record

ArticleScientific reports2017

Broad-Range Antiviral Activity of Hydrogen Sulfide Against Highly Pathogenic RNA Viruses.

Nikolay Bazhanov, Olivier Escaffre, Alexander N Freiberg, Roberto P Garofalo, Antonella Casola

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06294756 (Effects of Sulfurous Thermal Waters Inhalations on Long-COVID Syndrome), which is not on this map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06294756 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Sulfurous Thermal Waters Inhalations on Long-COVID Syndrome: a Double-blinded, Interventional, Randomized Case-control, Pilot Study on a Spa Centered Rehab Program

TypeinterventionalSponsorUniversity of Roma La SapienzaRan2023 to 2023Enrolled30ConditionsLong-COVID, Post COVID-19 Condition, Chronic COVID-19 Syndrome, Post Acute Sequelae of COVID-19ArmsInhalation of Sulfurous Thermal Water, Inhalation of Sterile Distilled non-pyrogenic Water
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Synthesis, HScientific reports · 2025
    Article
  5. Article
  6. Article
  7. The Triple Crown: NO, CO, and HPharmacology & therapeutics · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Utility of NO and HNitric oxide : biology and chemistry · 2022
    Review
  12. The Effects of HBiomedicines · 2022
    Article
  13. Article
  14. Reactive Sulfur Compounds in the Fight against COVID-19.Antioxidants (Basel, Switzerland) · 2022
    Review
  15. RefractoryJournal of clinical medicine · 2022
    Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nikolay BazhanovDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX, USA.
Olivier EscaffreDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
Alexander N FreibergDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
Roberto P GarofaloDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX, USA.
Antonella CasolaDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX, USA.
The University of Texas Medical Branch at Galveston · US

Funding

Virus, Tissue Culture and ImmunoassayP01AI062885 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI GAROFALO, ROBERTO P · 2005 to 2022
$23.9M
Innate Immune Response to Human Metapneumovirus InfectionR01AI079246 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CASOLA, ANTONELLA · 2010 to 2014
$1.9M
Role of Reactive Oxygen Species in Nipah Virus PathogenesisR21AI111042 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI FREIBERG, ALEXANDER NICLAS · 2014 to 2015
$426k
NIAID NIH HHS P01 AI062885NIAID NIH HHS R01 AI079246NIAID NIH HHS R21 AI111042
6 · The paper itself

Abstract

Hydrogen sulfide is an important endogenous mediator that has been the focus of intense investigation in the past few years, leading to the discovery of its role in vasoactive, cytoprotective and anti-inflammatory responses. Recently, we made a critical observation that H

Indexed as

AnimalsAnti-Inflammatory AgentsAntiviral AgentsCell LineCytokinesHumansHydrogen SulfideMorpholinesOrganothiophosphorus CompoundsRNA VirusesVirus ReplicationAnti-Inflammatory AgentsAntiviral AgentsCytokinesGYY 4137Hydrogen SulfideMorpholinesOrganothiophosphorus Compounds

Identifiers

PMID28106111
PMCPMC5247713
OpenAlexW2571716788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.