Evidence map›Paper›PMID 28106072›Full record

ArticleCell research2017

YTHDF3 facilitates translation and decay of N

Hailing Shi, Xiao Wang, Zhike Lu, Boxuan S Zhao, Honghui Ma, Phillip J Hsu, Chang Liu, Chuan He

Open access · bronzeAbstract read
In one paragraph

Article in Cell research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,193 papers.

0numbers the graph read from it
0cells of the map it votes in
1,193citing papers in PubMed
49.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,193 citing papers in PubMed, 1,844 citations in OpenAlex.

  1. Review
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  14. mExperimental and therapeutic medicine · 2026
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    Review
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  19. mNature reviews. Neuroscience · 2026
    Review
  20. Article

1,133 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hailing ShiDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA.
Xiao WangDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA.
Zhike LuDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA.
Boxuan S ZhaoDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA.
Honghui MaDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA.
Phillip J HsuDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA.
Chang LiuDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA.
Chuan HeDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA.
Howard Hughes Medical Institute · USUniversity of Chicago · US

Funding

Direct Oxidative Nucleic Acids DemethylationR01GM071440 · NIGMS · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2005 to 2018
$3.7M
Recognition and mechanism of N6-methyl adenosine modificationsR01GM113194 · NIGMS · UNIVERSITY OF CHICAGO · PI PAN, TAO · 2015 to 2022
$2.5M
NIGMS NIH HHS R01 GM071440NIGMS NIH HHS R01 GM113194
6 · The paper itself

Abstract

N

Indexed as

Protein BiosynthesisRNA StabilityAdenosineBase SequenceCytosolHeLa CellsHumansModels, BiologicalProtein BindingRNARNA-Binding ProteinsAdenosineN-methyladenosineRNARNA-Binding ProteinsYTHDF1 protein, humanYTHDF2 protein, humanYTHDF3 protein, human

Identifiers

PMID28106072
PMCPMC5339834
OpenAlexW2575691519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.