SynthesisBiomedical engineering online2016
Active lower limb prosthetics: a systematic review of design issues and solutions.
Synthesis in Biomedical engineering online, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05818410 (Human-Prosthetic Interaction), which is not on this map. Cited by 76 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Human-Prosthetic Interaction: Brain & Technology After Lower-Limb Loss
Who cites it
76 citing papers in PubMed, 2 syntheses or guidelines pooled it, 267 citations in OpenAlex.
- Therapeutic benefits of lower limb prostheses: a systematic review.Journal of neuroengineering and rehabilitation · 2023Pooled it
- EMG-driven control in lower limb prostheses: a topic-based systematic review.Journal of neuroengineering and rehabilitation · 2022Pooled it
- User accommodation to an active microprocessor-controlled knee in individuals with unilateral transfemoral amputation: a 5-week non-randomized trial.Journal of neuroengineering and rehabilitation · 2025Trial
- Using a microprocessor knee (C-Leg) with appropriate foot transitioned individuals with dysvascular transfemoral amputations to higher performance levels: a longitudinal randomized clinical trial.Journal of neuroengineering and rehabilitation · 2021Trial
- A new approach of inducing proprioceptive illusion by transcutaneous electrical stimulation.Journal of neuroengineering and rehabilitation · 2021Trial
- Design and Bench Evaluation of a Sensor-Integrated Prosthetic-Leg Prototype.Sensors (Basel, Switzerland) · 2026Article
- A multimodal EMG-IMU dataset and multi-dataset benchmark for deep learning-based human activity recognition.Scientific reports · 2026Article
- Cyberlegs X-Leg at CYBATHLON 2024: insights on the control development of an active transfemoral prosthesis.Journal of neuroengineering and rehabilitation · 2026Article
- Lower-limb prosthetic mechanisms: recent progress, control innovations and barriers to real-world adoption.Biomedical engineering online · 2026Review
- The SoftFoot Pro: an anthropomorphic and adaptive soft articulated prosthetic foot.Nature communications · 2026Article
- Using EMG Biofeedback to Restore Closed-Loop Neural Control on a Powered Prosthetic Ankle.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Compensation for balance disorders: analysis of this multifactorial process.European journal of translational myology · 2025Article
- Evidence-based recommendation of a powered knee for transfemoral bone-anchored prostheses: A cross-sectional study.Canadian prosthetics & orthotics journal · 2025Article
- Improving Device Testing Efficiency in Prosthetic Research: The Impact of an Automated Robustness Testing Protocol.Proceedings of the ... IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics. IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics · 2024Article
- Advantages of customization of osseointegrated implants in transfemoral amputees: a comparative analysis of surgical planning.Journal of orthopaedic surgery and research · 2024Article
- Transforming the Anthropomorphic Passive Free-Flow Foot Prosthesis Into a Powered Foot Prosthesis With Intuitive Control and Sensation (Bionic FFF).Military medicine · 2024Article
- ReliableFrontiers in bioengineering and biotechnology · 2024Article
- Article
- Development of four-bar polycentric knee joint with stance-phase knee flexion.Scientific reports · 2023Article
- Lower limb prosthetic prescription.Turkish journal of physical medicine and rehabilitation · 2023Review
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper presents a review on design issues and solutions found in active lower limb prostheses. This review is based on a systematic literature search with a methodical search strategy. The search was carried out across four major technical databases and the retrieved records were screened for their relevance. A total of 21 different active prostheses, including 8 above-knee, 9 below-knee and 4 combined knee-ankle prostheses were identified. While an active prosthesis may help to restore the functional performance of an amputee, the requirements regarding the actuation unit as well as for the control system are high and the development becomes a challenging task. Regarding mechanical design and the actuation unit high force/torque delivery, high efficiency, low size and low weight are conflicting goals. The actuation principle and variable impedance actuators are discussed. The control system is paramount for a "natural functioning" of the prosthesis. The control system has to enable locomotion and should react to the amputee's intent. For this, multi-level control approaches are reviewed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.