ArticleInsect molecular biology2017
Comparison of the proliferation and excretion of Bartonella quintana between body and head lice following oral challenge.
Article in Insect molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- DNA Barcoding of Head Lice from a ~1500-Year-Old Salt-Preserved Mummy from the Chehrabad Salt Mine, Iran.Insects · 2026Article
- Transcriptional induction of the IMD signaling pathway and associated antibacterial activity in the digestive tract of cat fleas (Ctenocephalides felis).Parasites & vectors · 2024Article
- Immune Reactions of Vector Insects to Parasites and Pathogens.Microorganisms · 2024Review
- POPULATION STRUCTURE AND BARTONELLA QUINTANA IN HEAD AND BODY LICE IN POKHARA, NEPAL (ANOPLURA: PEDICULIDAE).The Journal of parasitology · 2023Article
- Head lice as vectors of pathogenic microorganisms.Tropical medicine and health · 2023Review
- First Detection ofTropical medicine and infectious disease · 2023Article
- Exploring the potential role of defensins in differential vector competence of body and head lice for Bartonella quintana.Parasites & vectors · 2023Article
- Examination of vertical transmission of Bartonella quintana in body lice following multiple infectious blood meals.Pathogens and disease · 2022Article
- Putative native South Amerindian origin of head lice clade F: evidence from head lice nits infesting human shrunken heads.Scientific reports · 2022Article
- Head Lice Infestation in Schoolchildren, in Poland-Is There a Chance for Change?Journal of clinical medicine · 2022Article
- Molecular Characterization and Genetic Diversity of Haplogroup E Human Lice in Guinea, West Africa.Microorganisms · 2021Article
- Molecular identification of head lice collected in Franceville (Gabon) and their associated bacteria.Parasites & vectors · 2020Article
- Molecular investigation and genetic diversity of Pediculus and Pthirus lice in France.Parasites & vectors · 2020Article
- Genetic diversity of human head lice and molecular detection of associated bacterial pathogens in Democratic Republic of Congo.Parasites & vectors · 2019Article
- Human Bartonellosis: An Underappreciated Public Health Problem?Tropical medicine and infectious disease · 2019Review
- Where Are We With Human Lice? A Review of the Current State of Knowledge.Frontiers in cellular and infection microbiology · 2019Review
- Complexin in ivermectin resistance in body lice.PLoS genetics · 2018Article
- Detection of bacterial pathogens in clade E head lice collected from Niger's refugees in Algeria.Parasites & vectors · 2018Article
- RETRACTED: Body lice of homeless people reveal the presence of several emerging bacterial pathogens in northern Algeria.PLoS neglected tropical diseases · 2018Article
- Metazoan Parasite Vaccines: Present Status and Future Prospects.Frontiers in cellular and infection microbiology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Human body and head lice are highly related haematophagous ectoparasites but only the body louse has been shown to transmit Bartonella quintana, the causative agent of trench fever. The mechanisms by which body lice became a vector for B. quintana, however, are poorly understood. Following oral challenge, green fluorescent protein-expressing B. quintana proliferated over 9 days postchallenge with the number of bacteria being significantly higher in whole body vs. head lice. The numbers of B. quintana detected in faeces from infected lice, however, were approximately the same in both lice. Nevertheless, the viability of B. quintana was significantly higher in body louse faeces. Comparison of immune responses in alimentary tract tissues revealed that basal transcription levels of peptidoglycan recognition protein and defensins were lower in body lice and the transcription of defensin 1 was up-regulated by oral challenge with wild-type B. quintana in head but not in body lice. In addition, the level of cytotoxic reactive oxygen species generated by epithelial cells was significantly lower in body lice. Although speculative at this time, the reduced immune response is consistent with the higher vector competence seen in body vs. head lice in terms of B. quintana infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.