ArticleJournal of clinical laboratory analysis2017
Association of hematocrit with blood pressure and hypertension.
Article in Journal of clinical laboratory analysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 81 citations in OpenAlex.
- Article
- A machine learning-based framework for predicting hypertension using serum hematological factors.Scientific reports · 2026Article
- A Comparison of Machine Learning Algorithms for Predicting Hypertension Incidence Based on Cohort Study.Endocrinology, diabetes & metabolism · 2026Article
- Association Between Obesity Status and Hypertension Phenotypes: Are Inflammatory Indicators the Missing Link? Evidence From a Large Population Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Impact of smoking hookah and cigarettes on hematological and biochemical profiles in the Iranian population.Journal of health, population, and nutrition · 2026Article
- Short-term effects of haze exposure on clinical and subclinical cardiovascular indicators among adults in Nanjing.Scientific reports · 2026Article
- Male hypogonadism in patients on maintenance hemodiafiltration: prevalence and therapeutic effect.Frontiers in endocrinology · 2026Article
- Determinants and Clinical Impact of Visit-to-visit Blood Pressure Variability in Patients with Heart Failure with Preserved Ejection Fraction.JMA journal · 2025Article
- Association of serum levels and intakes of sodium and potassium with hypertension in the MASHAD cohort study population: a cross-sectional study.Journal of health, population, and nutrition · 2025Article
- Correlation analysis of hematocrit level and coronary heart disease in patients with chest pain: a case-control study.Journal of thoracic disease · 2025Article
- Beyond traditional metrics: evaluating the triglyceride-total cholesterol-body weight index (TCBI) in cardiovascular risk assessment.BMC cardiovascular disorders · 2025Article
- Article
- Testosterone Replacement Therapy: Effects on Blood Pressure in Hypogonadal Men.The world journal of men's health · 2024Article
- Hematological parameters of hypertensive patients in northeast Ethiopia: A comparative cross-sectional study.Heliyon · 2024Article
- White blood cell and platelet distribution widths are associated with hypertension: data mining approaches.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Association between hemoglobin concentration and hypertension risk in native Tibetans at high altitude.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Next-visit prediction and prevention of hypertension using large-scale routine health checkup data.PloS one · 2024Article
- A Real-World Study on the Short-Term Efficacy of Amlodipine in Treating Hypertension Among Inpatients.Pragmatic and observational research · 2024Article
- The association between red cell distribution width and newly diagnosed hypertension among adults in Northern Sudan: a case-control study.The Libyan journal of medicine · 2023Article
- The associations between hematological parameters and the incidence of prehypertension and hypertension in children and adolescents: a prospective cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
Corrections and comments
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Authors and funding
19 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertension (HTN) is a risk factor for stroke, renal failure, and cardiovascular disease. The association between biochemical and hematological parameters with high blood pressure may provide a more precise approach to risk prediction conferred by HTN in these patients.
objectiveThe aim of current study was to explore whether biochemical and hematological parameters are associated with HTN in a cohort study with a 7-year follow-up. MATERIALS AND
methodsA total of 9808 individuals were enrolled and recruited as part of the Mashhad Stroke and Heart Atherosclerotic Disorders (MASHAD) cohort study, and biochemical and hematological factors were measured in all subjects. Univariate and multivariate logistic regression analysis were performed to determine the association of biochemical and hematological parameters with HTN.
resultsSeveral biochemical parameters including fasting plasma glucose (FBG), serum high-sensitivity C-reactive protein (hs-CRP), triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and uric acid were increased in hypertensive participants. In contrast, serum high-density lipoprotein cholesterol (HDL-C) was lower in hypertensive individuals. Furthermore, we demonstrated that hematological parameters including white blood cell (WBC) count, red blood cell (RBC) count, hemoglobin (HGB), hematocrit (HCT), and mean corpuscular hemoglobin (MCH) were higher in the hypertensive group compared to the control group. But mean corpuscular volume (MCV), and red cell distribution width (RDW), were decreased in the hypertensive group. Furthermore, our results strongly suggested that among these parameters, hematocrit was the independent risk factor for hypertension in the population.
conclusionWe demonstrated the association of altered biochemical and hematological factors with hypertension supporting the value of emerging markers for early prediction of high blood pressure in prone individuals.
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