Evidence map›Paper›PMID 28105511›Full record

ArticleCalcified tissue international2017

Bone Density in the Obese Child: Clinical Considerations and Diagnostic Challenges.

Jennifer C Kelley, Nicola Crabtree, Babette S Zemel

Abstract read
In one paragraph

Article in Calcified tissue international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. The role of bone health in low-velocity fractures and the effects of obesity on the growing skeleton.Journal of the Pediatric Orthopaedic Society of North America · 2024
    Article
  5. Review
  6. Review
  7. Obesity and Bone: A Complex Relationship.International journal of molecular sciences · 2021
    Review
  8. Article
  9. The Bones of Children With Obesity.Frontiers in endocrinology · 2020
    Review
  10. Review
  11. Article
  12. Article
  13. The Role of Obesity in Pediatric Orthopedics.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. [Review of high-resolution peripheral quantitative computed tomography for the assessment of bone microstructure and strength].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2018
    Review
  18. Article
  19. Fat and bone in children - where are we now?Annals of pediatric endocrinology & metabolism · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Jennifer C KelleyDivision of Endocrinology and Diabetes, Monroe Carell, Jr Children's Hospital at Vanderbilt, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA.
Nicola CrabtreeDepartment of Endocrinology and Diabetes, Birmingham Children's Hospital, Birmingham, UK.
Babette S ZemelDivision of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, 3535 Market Street, Room 1560, Philadelphia, PA, 19104, USA. zemel@email.chop.edu.
Birmingham Children's Hospital · GBChildren's Hospital of Philadelphia · USVanderbilt University · US

Funding

Translational Research Training in Pediatric Diabetes & EndocrinologyT32DK063688 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI LORRAINE E LEVITT KATZ, ANDREA Bridget KELLY · 2002 to 2026
$5.4M
Bone Health of Obese Adolescents During Weight LossR01HD049701 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ZEMEL, BABETTE S · 2007 to 2011
$3.2M
Department of Health HCS/P10/009NICHD NIH HHS R01 HD049701NIDDK NIH HHS T32 DK063688
6 · The paper itself

Abstract

The prevalence of obesity in children has reached epidemic proportions. Concern about bone health in obese children, in part, derives from the potentially increased fracture risk associated with obesity. Additional risk factors that affect bone mineral accretion, may also contribute to obesity, such as low physical activity and nutritional factors. Consequences of obesity, such as inflammation, insulin resistance, and non-alcoholic fatty liver disease, may also affect bone mineral acquisition, especially during the adolescent years when rapid increases in bone contribute to attaining peak bone mass. Further, numerous pediatric health conditions are associated with excess adiposity, altered body composition, or endocrine disturbances that can affect bone accretion. Thus, there is a multitude of reasons for considering clinical assessment of bone health in an obese child. Multiple diagnostic challenges affect the measurement of bone density and its interpretation. These include greater precision error, difficulty in positioning, and the effects of increased lean and fat tissue on bone health outcomes. Future research is required to address these issues to improve bone health assessment in obese children.

Indexed as

Absorptiometry, PhotonBody CompositionBone DensityChildFemaleHumansMaleObesityBody compositionChildrenDual-energy X-ray absorptiometryFractureObesityPeripheral quantitative computed tomography

Identifiers

PMID28105511
PMCPMC5395312
OpenAlexW2574603349

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.