Evidence map›Paper›PMID 28105500›Full record

ReviewZeitschrift fur Gerontologie und Geriatrie2017

[Discontinuation of benzodiazepines in old age : When and if so, how?]

Dirk K Wolter

Abstract readReview
PubMed Publisher
In one paragraph

Review in Zeitschrift fur Gerontologie und Geriatrie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. [Early onset substance abuse disorders and addictive diseases in old age].Zeitschrift fur Gerontologie und Geriatrie · 2018
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Dirk K WolterGerontopsykiatrisk Afdeling, Psykiatrien, Kresten Philipsens Vej 15 B, 6200, Aabenraa, Dänemark. dirk.wolter@rsyd.dk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although viewed critically in geriatrics, benzodiazepine use is still common among old people. Before reducing the dosage the following questions must be considered: 1. Are there indications for benzodiazepine treatment and will discontinuation cause relevant rebound symptoms of the initial disorder treated? 2. To what extent do the patient and other key persons consider discontinuation to be reasonable and will they support discontinuation? 3. Is the target complete withdrawal, a dose reduction or shift to another benzodiazepine drug which is more suitable in old age for pharmacokinetic reasons? This article provides assistance in answering these questions and some guidelines for the practical management of discontinuation. It is mandatory 1) to periodically address the problem of long-term benzodiazepine use when counseling the patient and key persons and 2) to be aware that several intermediate steps exist between continuation and complete discontinuation, which may be considered successful treatment.

Indexed as

Drug Administration ScheduleAgedAged, 80 and overAnti-Anxiety AgentsAnxiety DisordersBenzodiazepinesDose-Response Relationship, DrugDrug MonitoringEvidence-Based MedicineFemaleGeriatric AssessmentGermanyHumansMaleSubstance Withdrawal SyndromeTreatment OutcomeAnti-Anxiety AgentsBenzodiazepinesAnxiety disordersDiscontinuation programIntoxicationWithdrawalZ-drugs

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.