SynthesisBioMed research international2016
Gray Matter Atrophy within the Default Mode Network of Fibromyalgia: A Meta-Analysis of Voxel-Based Morphometry Studies.
Synthesis in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of voxel-based morphometric studies of fibromyalgia.Frontiers in neuroscience · 2023Pooled it
- Brain imaging-wide exploration of site-specific pain: genetic correlation and Mendelian randomization study.Psychological medicine · 2026Article
- Moving Toward Objective Diagnosis in Fibromyalgia: Emerging Biomarkers and Digital Phenotyping Tools.Biomedicines · 2026Review
- Alterations in cortical surface morphometry in fibromyalgia: a multi-parametric study.Frontiers in psychology · 2026Article
- Major depressive disorder in fibromyalgia: novel insights from resting-state functional connectivity analysis.The Korean journal of pain · 2025Article
- Juvenile Primary Fibromyalgia Syndrome: Advances in Etiopathogenesis, Clinical Assessment and Treatment: A Narrative Review.Biomedicines · 2025Review
- Metformin and fibromyalgia pathophysiology: current insights and promising future therapeutic strategies.Molecular biology reports · 2024Review
- Psychological characteristics associated with the brain volume of patients with fibromyalgia.BioPsychoSocial medicine · 2023Article
- Multimodal non-invasive non-pharmacological therapies for chronic pain: mechanisms and progress.BMC medicine · 2023Review
- Brain structural correlates of postoperative axial pain in degenerative cervical myelopathy patients following posterior cervical decompression surgery: a voxel-based morphometry study.BMC medical imaging · 2023Article
- Brain Structural Changes During Juvenile Fibromyalgia: Relationships With Pain, Fatigue, and Functional Disability.Arthritis & rheumatology (Hoboken, N.J.) · 2022Article
- Effects of Acupuncture Therapy on Drug-Resistant Fibromyalgia: An Exploratory Single-Arm Nonrandomized Trial.Medical acupuncture · 2022Article
- CNS imaging characteristics in fibromyalgia patients with and without peripheral nerve involvement.Scientific reports · 2022Article
- Article
- Differences in Structural Brain Characteristics Between Individuals with Chronic Nonspecific Neck Pain and Asymptomatic Controls: A Case-Control Study.Journal of pain research · 2022Article
- Observational
- Fibromyalgia Detection Based on EEG Connectivity Patterns.Journal of clinical medicine · 2021Article
- Impact of Fibromyalgia in the Hippocampal Subfields Volumes of Women-An MRI Study.International journal of environmental research and public health · 2021Article
- Complex Regional Pain Syndrome: Thalamic GMV Atrophy and Associations of Lower GMV With Clinical and Sensorimotor Performance Data.Frontiers in neurology · 2021Article
- Ceftriaxone inhibits stress-induced bladder hyperalgesia and alters cerebral micturition and nociceptive circuits in the rat: A multidisciplinary approach to the study of urologic chronic pelvic pain syndrome research network study.Neurourology and urodynamics · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the years, studies have demonstrated morphological changes in the brain of fibromyalgia (FMS). We aimed to conduct a coordinate-based meta-analytic research through systemic review on voxel-based morphometry (VBM) imaging results to identify consistent gray matter (GM) difference between FMS patients and healthy subjects. We performed a comprehensive literature search in PubMed (January 2000-December 2015) and included six VBM publication on FMS. Stereotactic data were extracted from 180 patients of FMS and 123 healthy controls. By means of activation likelihood estimation (ALE) technique, regional GM reduction in left medial prefrontal cortex and right dorsal posterior cingulate cortex was identified. Both regions are within the default mode network. In conclusion, the gray matter deficit is related to the both affective and nonaffective components of pain processing. This result also provided the neuroanatomical correlates for emotional and cognitive symptoms in FMS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.