Evidence map›Paper›PMID 28105257›Full record

ArticleWorld journal of hepatology2017

Ultrasound shear wave elastography and liver fibrosis: A Prospective Multicenter Study.

Joyce Anyona Sande, Suleman Verjee, Sudhir Vinayak, Farin Amersi, Munir Ghesani

Abstract read
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Article in World journal of hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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  19. Ultrasonic technologies in imaging and drug delivery.Cellular and molecular life sciences : CMLS · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joyce Anyona SandeJoyce Anyona Sande, Sudhir Vinayak, Department of Radiology, Aga Khan University Hospital, Nairobi 30270-00100, Kenya.
Suleman VerjeeJoyce Anyona Sande, Sudhir Vinayak, Department of Radiology, Aga Khan University Hospital, Nairobi 30270-00100, Kenya.
Sudhir VinayakJoyce Anyona Sande, Sudhir Vinayak, Department of Radiology, Aga Khan University Hospital, Nairobi 30270-00100, Kenya.
Farin AmersiJoyce Anyona Sande, Sudhir Vinayak, Department of Radiology, Aga Khan University Hospital, Nairobi 30270-00100, Kenya.
Munir GhesaniJoyce Anyona Sande, Sudhir Vinayak, Department of Radiology, Aga Khan University Hospital, Nairobi 30270-00100, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the accuracy of shear wave elastography (SWE) alone and in combination with aminotransferase platelet ratio index (APRI) score in the staging of liver fibrosis.

methodsA multicenter prospective study was conducted to assess the accuracy of SWE (medians) and APRI to predict biopsy results. The analysis focused on distinguishing the different stages of liver disease, namely, F0 from F1-4, F0-1 from F2-4, F0-2 from F3-4 and F0-3 from F4; F0-F1 from F2-F4 being of primary interest. The area under the receiver operating characteristic (AUROC) curve was computed using logistic regression model. The role of age, gender and steatosis was also assessed.

resultsSWE alone accurately distinguished F0-1 from F2-4 with a high probability. The AUROC using SWE alone was 0.91 compared to 0.78 for using the APRI score alone. The APRI score, when used in conjunction with SWE, did not make a significant contribution to the AUROC. SWE and steatosis were the only significant predictors that differentiated F0-1 from F2-4 with an AUROC of 0.944.

conclusionOur study validates the use of SWE in the diagnosis and staging of liver fibrosis. Furthermore, the probability of a correct diagnosis is significantly enhanced with the addition of steatosis as a prognostic factor.

Indexed as

Aminotransferase platelet rationLiver biopsyLiver fibrosisShear wave elastography

Identifiers

PMID28105257
PMCPMC5220270

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.