Evidence map›Paper›PMID 28105253›Full record

ArticleOxidative medicine and cellular longevity2016

Demethoxycurcumin Preserves Renovascular Function by Downregulating COX-2 Expression in Hypertension.

Yingjuan Li, Danyang Tian, Chunhua Zhu, Liqun Ren

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Discovery of Pyrazolo[4,3-Molecules (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yingjuan LiDepartment of Geriatrics, Zhongda Hospital, Medical School, Southeast University, 87# Ding Jiaqiao, Nanjing 210009, China.ORCID 0000-0002-5580-1003
Danyang TianDepartment of Physiology, Hebei Medical University, Shi Jiazhuang 050017, China.ORCID 0000-0002-4553-0115
Chunhua ZhuDepartment of Neurology, Second Hospital of Hebei Medical University, Shi Jiazhuang 050017, China.ORCID 0000-0002-6302-4267
Liqun RenDepartment of Geriatrics, Zhongda Hospital, Medical School, Southeast University, 87# Ding Jiaqiao, Nanjing 210009, China.ORCID 0000-0002-1132-8613
Hebei Medical University · CNZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension-associated endothelial dysfunction is largely due to the exaggerated vasoconstrictor generation by cyclooxygenase-2 (COX-2). COX-2 is induced under inflammatory condition. Demethoxycurcumin (DMC) is a major component of

Indexed as

AcetylcholineAgedAngiotensin IIAnimalsBlood PressureCelecoxibCurcumaCurcuminCyclooxygenase 2DiarylheptanoidsDown-RegulationEndothelium, VascularHumansHuman Umbilical Vein Endothelial CellsHypertensionMaleAcetylcholineAngiotensin IICelecoxibCurcuminCyclooxygenase 2demethoxycurcuminDiarylheptanoidsNitric OxideNitric Oxide Synthase Type III

Identifiers

PMID28105253
PMCPMC5220467
OpenAlexW2565978719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.