Evidence map›Paper›PMID 28105163›Full record

ArticleOncology letters2016

Selection of antitumor displayed peptides for the specific delivery of the anticancer drug lactaptin.

Anna Andreevna Nemudraya, Elena Vladimirovna Kuligina, Alexandr Alexeevich Ilyichev, Alexandr Sergeevich Fomin, Grigory Alexandrovich Stepanov, Anna Valentinovna Savelyeva, Olga Alexandrovna Koval, Vladimir Alexandrovich Richter

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anna Andreevna NemudrayaLaboratory of Biotechnology, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of The Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Elena Vladimirovna KuliginaLaboratory of Biotechnology, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of The Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Alexandr Alexeevich IlyichevDepartment of Bioengineering, State Research Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia; Department of Biology, Faculty of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.
Alexandr Sergeevich FominLaboratory of Biotechnology, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of The Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Grigory Alexandrovich StepanovLaboratory of Biotechnology, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of The Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Anna Valentinovna SavelyevaLaboratory of Biotechnology, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of The Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Olga Alexandrovna KovalLaboratory of Biotechnology, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of The Russian Academy of Sciences, 630090 Novosibirsk, Russia; Department of Biology, Faculty of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.
Vladimir Alexandrovich RichterLaboratory of Biotechnology, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of The Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Siberian Branch of the Russian Academy of Sciences · RUInstitute of Chemical Biology and Fundamental Medicine · RUState Research Center of Virology and Biotechnology VECTOR · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been previously demonstrated that lactaptin, the proteolytic fragment of human milk protein κ-casein, induces the death of various cultured cancer cells. The recombinant analog of lactaptin, RL2, effectively induces the apoptosis of mouse hepatocarcinoma-1 (HA-1) tumor cells

Indexed as

apoptosisfusion proteinslactaptintargeted deliverytumor-specific peptides

Identifiers

PMID28105163
PMCPMC5228560
OpenAlexW2530379476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.