Evidence map›Paper›PMID 28105104›Full record

ArticleExperimental and therapeutic medicine2016

Glucocorticoids regulate the proliferation of T cells via miRNA-155 in septic shock.

Ying Chen, Guang Wang, Zhongmin Liu, Shiji Wang, Yushan Wang

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Glucocorticoid Effect in Cancer Patients.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. The role of microRNAs in glucocorticoid action.The Journal of biological chemistry · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ying ChenIntensive Care Unit, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Guang WangIntensive Care Unit, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Zhongmin LiuIntensive Care Unit, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Shiji WangIntensive Care Unit, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Yushan WangIntensive Care Unit, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
First Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although previous studies have evaluated the roles of glucocorticoids and lymphocytes in septic shock, the precise mechanism remains unclear. The present study focused on investigating the influence of glucocorticoids on micro (mi)RNA-155 expression levels and the proliferation of T lymphocytes in septic shock. T cells were harvested from in the peripheral blood of patients with septic shock and healthy volunteers and were cultured

Indexed as

glucocorticoidslymphocytemiRNA-155septic shock

Identifiers

PMID28105104
PMCPMC5228347
OpenAlexW2535761310

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.