ArticleWorld journal of gastroenterology2017
Novel CagA ELISA exhibits enhanced sensitivity of
Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Prevalence of Helicobacter pylori cagA virulence factor and validation of serological tests in a population from Northeastern Brazil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
- Multiplex Accelerated PCR System for One-Step Helicobacter pylori cagA + Genotypes Detection: A Guide for Clinical Testing.Current microbiology · 2022Article
- Assessment of the diagnostic accuracy and relevance of a novel ELISA system developed for seroepidemiologic surveys of Helicobacter pylori infection in African settings.PLoS neglected tropical diseases · 2021Article
- Endoscopy-based Kyoto classification score of gastritis related to pathological topography of neutrophil activity.World journal of gastroenterology · 2020Article
- Characterization of a novel Helicobacter pylori East Asian-type CagA ELISA for detecting patients infected with various cagA genotypes.Medical microbiology and immunology · 2020Article
- Epitope peptides of Helicobacter pylori CagA antibodies from sera by whole-peptide mapping.Journal of gastroenterology · 2019Article
- Designing a novel ELISA method based onGastroenterology and hepatology from bed to bench · 2018Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo develop a novel
methodsRecombinant East Asian-type CagA protein was purified and immobilized for ELISA. Serum samples from 217 Vietnamese individuals (110
resultsRecombinant 70-100 kDa fragments were immobilized on the ELISA plate. In ROC analysis, the area under the curve of our East Asian-type CagA ELISA was comparable to that of conventional CagA ELISA. The sensitivity of the two ELISAs differed depending on the
conclusionThe novel ELISA is useful to detect anti-CagA antibodies in East Asian countries, and the titer may be a marker for predicting chronic gastritis.
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Registered trials
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