Evidence map›Paper›PMID 28104834›Full record

ArticleStroke2017

Disparities in the Use of Seizure Medications After Intracerebral Hemorrhage.

Andrew M Naidech, Paloma Toledo, Shyam Prabhakaran, Jane L Holl

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Stroke, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Why Physicians Prescribe Prophylactic Seizure Medications after Intracerebral Hemorrhage: An Adaptive Conjoint Analysis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2020
    Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrew M NaidechFrom the Department of Neurology (A.M.N., S.P.), and Department of Obstetrics and Gynecology (P.T.), Northwestern University Center for Healthcare Studies, Institute for Public Health and Medicine (J.L.H.), Chicago, IL. a-naidech@northwestern.edu.
Paloma ToledoFrom the Department of Neurology (A.M.N., S.P.), and Department of Obstetrics and Gynecology (P.T.), Northwestern University Center for Healthcare Studies, Institute for Public Health and Medicine (J.L.H.), Chicago, IL.
Shyam PrabhakaranFrom the Department of Neurology (A.M.N., S.P.), and Department of Obstetrics and Gynecology (P.T.), Northwestern University Center for Healthcare Studies, Institute for Public Health and Medicine (J.L.H.), Chicago, IL.
Jane L HollFrom the Department of Neurology (A.M.N., S.P.), and Department of Obstetrics and Gynecology (P.T.), Northwestern University Center for Healthcare Studies, Institute for Public Health and Medicine (J.L.H.), Chicago, IL.
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
NRSA INSTITUTIONAL TRAINING GRANTT32HS000078 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HOLL, JANE LOUISE · 1998 to 2018
$5.6M
Mechanisms of Early Recurrence in Intracranial Atherosclerotic DiseaseR01NS084288 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LIEBESKIND, DAVID SIGMUND, PRABHAKARAN, SHYAM · 2014 to 2018
$3.0M
Stroke Trials Network - Regional Coordinating Stroke CentersU10NS086608 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PRABHAKARAN, SHYAM · 2013 to 2017
$1.8M
Health related quality of life and seizure medications after hemorrhagic strokeK18HS023437 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NAIDECH, ANDREW M · 2015 to 2016
$357k
AHRQ HHS K18 HS023437AHRQ HHS T32 HS000078NCATS NIH HHS UL1 TR001422NICHD NIH HHS HHSN275201200025CNINDS NIH HHS R01 NS084288NINDS NIH HHS U10 NS086608
6 · The paper itself

Abstract

background and purposeWe investigated potential disparities in the use of prophylactic seizure medications in patients with intracerebral hemorrhage.

methodsReview of multicenter electronic health record (EHR) data with simultaneous prospective data recording. EHR data were retrieved from HealthLNK, a multicenter EHR repository in Chicago, Illinois, from 2006 to 2012 (multicenter cohort). Additional data were prospectively coded (single-center cohort) from 2007 through 2015.

resultsThe multicenter cohort comprised 3422 patients from 4 HealthLNK centers. Use of levetiracetam varied by race/ethnicity (

conclusionsAlthough multicenter EHR data showed apparent racial/ethnic disparities in the use of prophylactic seizure medications, a more complete single-center cohort found the apparent disparity to be confounded by the clinical factors of hypertension and hematoma location. Disparities in care after intracerebral hemorrhage are common; however, administrative data may lead to the discovery of disparities that are confounded by detailed clinical data not readily available in EHRs.

Indexed as

AdultAgedAged, 80 and overAge FactorsCerebral HemorrhageFemaleHumansHypertensionMaleMiddle AgedProspective StudiesRacial GroupsRisk FactorsSeizuresTreatment Outcomebraincerebral hemorrhagecritical careprivacystroke

Identifiers

PMID28104834
PMCPMC5330899
OpenAlexW2573872126

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.