ArticleEnvironmental research2017
Serum perfluoroalkyl substances in children exposed to the world trade center disaster.
Article in Environmental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Human exposure pathways to poly- and perfluoroalkyl substances (PFAS) from indoor media: A systematic review.Environment international · 2022Pooled it
- DNA Methylation as a Molecular Mechanism of Carcinogenesis in World Trade Center Dust Exposure: Insights from a Structured Literature Review.Biomolecules · 2024Review
- Association of exposure to multiple perfluoroalkyl and polyfluoroalkyl substances and glucose metabolism in National Health and Nutrition Examination Survey 2017-2018.Frontiers in public health · 2024Article
- Characteristics of Cancers in Community Members Exposed to the World Trade Center Disaster at a Young Age.International journal of environmental research and public health · 2022Article
- Scientific Value of the Sub-Cohort of Children in the World Trade Center Health Registry.International journal of environmental research and public health · 2022Article
- Posttraumatic Stress Disorder Mediates the Association between Traumatic World Trade Center Dust Cloud Exposure and Ongoing Systemic Inflammation in Community Members.International journal of environmental research and public health · 2022Article
- Molecular Clustering Analysis of Blood Biomarkers in World Trade Center Exposed Community Members with Persistent Lower Respiratory Symptoms.International journal of environmental research and public health · 2022Article
- Polybrominated Diphenyl Ethers (PBDEs) in Marine Fish and Dietary Exposure in Newfoundland.EcoHealth · 2022Article
- Hospitalizations among World Trade Center Health Registry Enrollees Who Were under 18 Years of Age on 9/11, 2001-2016.International journal of environmental research and public health · 2021Article
- Lung Cancer Characteristics in the World Trade Center Environmental Health Center.International journal of environmental research and public health · 2021Article
- The Development of a WTC Environmental Health Center Pan-Cancer Database.International journal of environmental research and public health · 2021Article
- The association between prenatal exposure to perfluoroalkyl substances and childhood neurodevelopment.Environmental pollution (Barking, Essex : 1987) · 2020Article
- Serum perfluoroalkyl substances and lung function in adolescents exposed to the World Trade Center disaster.Environmental research · 2019Article
- Cord blood perfluoroalkyl substances in mothers exposed to the World Trade Center disaster during pregnancy.Environmental pollution (Barking, Essex : 1987) · 2019Article
- Respiratory Health and Lung Function in Children Exposed to the World Trade Center Disaster.The Journal of pediatrics · 2018Article
- Adolescents exposed to the World Trade Center collapse have elevated serum dioxin and furan concentrations more than 12years later.Environment international · 2018Article
- Cardiometabolic profiles of adolescents and young adults exposed to the World Trade Center Disaster.Environmental research · 2018Article
- Serum perfluoroalkyl substances and cardiometabolic consequences in adolescents exposed to the World Trade Center disaster and a matched comparison group.Environment international · 2017Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
The World Trade Center (WTC) disaster released large amounts of various chemical substances into the environment, including perfluoroalkyl substances (PFASs). Yet, no studies have examined exposures in children living or attending schools near the disaster site. We measured serum PFASs in WTC Health Registry (WTCHR) respondents who were ≤8 years of age on September 11, 2001 and a sociodemographically-matched comparison group. We also examined the relationship of PFASs levels with dust cloud exposure; home dust exposure, and with traumatic exposure, the latter to take into account differences related to possible mental health consequences and associated behavioral problems. Serum samples, collected between 2014 and 2016, were analyzed from 123 WTCHR participants and from 185 participants in the comparison group. In the WTCHR group, median perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) levels were 1.81ng/mL and 3.72ng/mL, respectively. Controlling for sex, caloric intake, race/ethnicity, and date of birth, significant increases among WTCHR participants compared with the matched comparison group were detected for perfluorohexanesulfonate (0.23ng/mL increase or 0.24log unit increase, p=0.006); PFOS (0.86ng/mL increase or 0.16log unit increase, p=0.011); PFOA (0.35ng/mL increase or 0.18log unit increase, p<0.001); perfluorononanoic acid (0.12ng/mL increase or 0.17log unit increase, p=0.003); perfluorodecanoic acid (0.06ng/mL increase or 0.42log unit increase, p<0.001); and perfluoroundecanoic acid (0.03ng/mL increase or 0.32log unit increase, p=0.019). Stronger associations were identified for home dust exposures and traumatic exposures than dust cloud. These findings highlight the importance of conducting longitudinal studies in this population to assess possible cardiometabolic and renal consequences related to these exposures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.