Evidence map›Paper›PMID 28104285›Full record

ArticleTrends in neurosciences2017

Resisting the Urge to Act: DREADDs Modifying Habits.

Mark A G Eldridge, Barry J Richmond

Erratum issuedAbstract readComment
In one paragraph

Article in Trends in neurosciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Mark A G EldridgeSection on Neural Coding and Computation, Laboratory of Neuropsychology, Bldg 49, Rm 1B80, NIMH/NIH/DHHS, Bethesda, MD, USA. Electronic address: Mark.Eldridge@nih.gov.
Barry J RichmondSection on Neural Coding and Computation, Laboratory of Neuropsychology, Bldg 49, Rm 1B80, NIMH/NIH/DHHS, Bethesda, MD, USA. Electronic address: Barry.Richmond@nih.gov.

Funding

Neural Mechanisms Of Motivation And RewardZIAMH002619 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI RICHMOND, BARRY J · 2009 to 2025
$21.3M
NEURAL MECHANISMS OF MOTIVATION AND REWARDZ01MH002619 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI RICHMOND, BARRY J · 1992 to 2008
$2.7M
Intramural NIH HHS Z01 MH002619
6 · The paper itself

Abstract

Recently, Meyer and Bucci used chemogenetic technology - artificial excitatory and inhibitory receptors - to modulate neuronal activity in two connected brain regions in opposite directions simultaneously. This innovative manipulation revealed that the two regions studied, orbitofrontal cortex and nucleus accumbens, are not sequentially dependent during contextual decision-making.

Indexed as

Decision MakingHabitsNerve NetNucleus AccumbensPrefrontal CortexAnimalsHumansReward

Identifiers

PMID28104285
PMCPMC5285454

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.