ArticleBMC complementary and alternative medicine2017
Pharmacological profile of the aerial parts of Rubus ulmifolius Schott.
Article in BMC complementary and alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
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- Inhibition of α-Glucosidase Activity and Islet Amyloid PolyPeptide Fibril Formation byPlants (Basel, Switzerland) · 2025Article
- Therapeutic Insights intoPharmaceuticals (Basel, Switzerland) · 2025Article
- Cardiovascular Effects, Antioxidant Activity, and Phytochemical Analysis ofPlants (Basel, Switzerland) · 2025Article
- Changes in Bioactive and Physicochemical Composition of Rubus During Three Developmental Stages.Plant foods for human nutrition (Dordrecht, Netherlands) · 2025Article
- In Vitro and In Silico Biological Activities Investigation of Ethyl Acetate Extract ofPlants (Basel, Switzerland) · 2024Article
- Evidence-Based Anti-Diabetic Properties of Plant from the Occitan Valleys of the Piedmont Alps.Pharmaceutics · 2022Review
- Isolation of Phenolic Compounds from Raspberry Based on Molecular Imprinting Techniques and Investigation of Their Anti-Alzheimer's Disease Properties.Molecules (Basel, Switzerland) · 2022Article
- Study on SupergenusPlants (Basel, Switzerland) · 2022Review
- Evaluation of antinociceptive activity of Ilex dipyrena Wall. in mice.BMC complementary medicine and therapies · 2021Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAs aerial parts of Rubus ulmifolius contains phytochemicals like flavonoids and tannins. And whereas flavonoids and tannins have antioxidant and antipyretic activity, hence, current work is carried out to screen crude methanolic extract of aerial parts of Rubus ulmifolius (Ru.Cr) and crude flavonoids rich extract of Rubus ulmifolius (Ru.F) for possible antioxidant and antipyretic activity. Ru.Cr and Ru.F are also tested for brine shrimps lethality bioassay. Ru.F is tested for the first time for possible antioxidant and antipyretic activity.
methodsPreliminary phytochemical screening of Ru.Cr and Ru.F was performed as it provides rapid finger printing for targeting a pharmacological activity. Acute toxicity and Brine shrimps' cytotoxicity studies of Ru.Cr and Ru.F were performed to determine its safe dose range. Antioxidant and antipyretic studies were also performed as per reported procedures.
resultsRu.Cr tested positive for presence of tannins, alkaloids, flavonoids and steroids. Ru.Cr is safe up to 6 g/kg following oral doses for acute toxicity study. Ru.Cr is safe up to 75 μg/kg (p.o), LC
conclusionsThe current work confirms that aerial parts of Rubus ulmifolius contain flavonoids that are safe up to 6 g/kg (p.o). Crude methanolic extract and flavonoids rich fraction of Rubus ulmifolius have significant antioxidant and antipyretic activity. Further work is required to isolate the pharmacologically active substances for relatively safe and effective antipyretics and antioxidants.
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