ArticleBMC microbiology2017
Genomic and transcriptomic comparison between Staphylococcus aureus strains associated with high and low within herd prevalence of intra-mammary infection.
Article in BMC microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 65 citations in OpenAlex.
- Microbiological Quality of Maize Silage in Relation to Agricultural Practices: A Four-Year Study.Foods (Basel, Switzerland) · 2026Article
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- Virulence traits, agr typing, multidrug resistance patterns, and biofilm ability of MDR Staphylococcus aureus recovered from clinical and subclinical mastitis in dairy cows.BMC microbiology · 2025Article
- In Vitro Adhesion and Invasion Rates ofVeterinary sciences · 2025Article
- An Investigation of Virulence Genes ofAnimals : an open access journal from MDPI · 2024Article
- The secretome of Staphylococcus aureus strains with opposite within-herd epidemiological behavior affects bovine mononuclear cell response.Veterinary research · 2023Article
- BovineFrontiers in veterinary science · 2023Article
- Comparative secretome analysis ofVirulence · 2022Article
- Forecasting Staphylococcus aureus Infections Using Genome-Wide Association Studies, Machine Learning, and Transcriptomic Approaches.mSystems · 2022Article
- Diversity and pathogenesis of Staphylococcus aureus from bovine mastitis: current understanding and future perspectives.BMC veterinary research · 2022Review
- Within-Host Adaptation ofInternational journal of molecular sciences · 2021Article
- Investigation and Follow-Up of a Staphylococcal Food Poisoning Outbreak Linked to the Consumption of Traditional Hand-Crafted Alm Cheese.Pathogens (Basel, Switzerland) · 2020Article
- Interrogating the Whole-Genome Shotgun Sequence of Escherichia coli Sequence Type 127 Strain 1538RHQ, Which Harbors Virulent Antigenic Factors, Isolated from a Mastitic Cow.Microbiology resource announcements · 2019Article
- Digital gene expression analyses of mammary glands from meat ewes naturally infected with clinical mastitis.Royal Society open science · 2019Article
- Comparative genomics of Staphylococcus aureus associated with subclinical and clinical bovine mastitis.PloS one · 2019Article
- Distinct phenotypic traits of Staphylococcus aureus are associated with persistent, contagious bovine intramammary infections.Scientific reports · 2018Article
- Adaptive molecular evolution ofEcology and evolution · 2017Article
- Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus aureus (Staph. aureus) is one of the major pathogens causing mastitis in dairy ruminants worldwide. The chronic nature of Staph. aureus infection enhances the contagiousness risk and diffusion in herds. In order to identify the factors involved in intra-mammary infection (IMI) and diffusion in dairy cows, we investigated the molecular characteristics of two groups of Staph. aureus strains belonging to ST8 and ST398, differing in clinical properties, through comparison of whole genome and whole transcriptome sequencing.
resultsThe two groups of strains, one originated from high IMI prevalence herds and the other from low IMI prevalence herds, present a peculiar set of genes and polymorphisms related to phenotypic features, such as bacterial invasion of mammary epithelial cells and host adaptation. Transcriptomic analysis supports the high propensity of ST8 strain to chronicity of infection and to a higher potential cytotoxicity.
conclusionsOur data are consistent with the invasiveness and host adaptation feature for the strains GTB/ST8 associated to high within-herd prevalence of mastitis. Variation in genes coding for surface exposed proteins and those associated to virulence and defence could constitute good targets for further research.
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