Evidence map›Paper›PMID 28103717›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2017

Baccharis trimera inhibits reactive oxygen species production through PKC and down-regulation p47

Glaucy Rodrigues de Araújo, Ana Carolina Silveira Rabelo, Janaína Serenato Meira, Joamyr Victor Rossoni-Júnior, William de Castro-Borges, Renata Guerra-Sá, Maurício Azevedo Batista, Denise da Silveira-Lemos, Gustavo Henrique Bianco de Souza, Geraldo Célio Brandão and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Hypoglycemic activities of flowers ofChinese herbal medicines · 2024
    Article
  3. Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  4. Evidence-based complementary and alternative medicine : eCAM · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Glaucy Rodrigues de Araújo1 Center for Research in Biological Sciences - NUPEB, Federal University of Ouro Preto, 35400-000 Ouro Preto, Brazil.
Ana Carolina Silveira Rabelo2 Department of Biological Sciences, Federal University of Ouro Preto, 35400-000 Ouro Preto, Brazil.
Janaína Serenato Meira2 Department of Biological Sciences, Federal University of Ouro Preto, 35400-000 Ouro Preto, Brazil.
Joamyr Victor Rossoni-Júnior1 Center for Research in Biological Sciences - NUPEB, Federal University of Ouro Preto, 35400-000 Ouro Preto, Brazil.
William de Castro-Borges1 Center for Research in Biological Sciences - NUPEB, Federal University of Ouro Preto, 35400-000 Ouro Preto, Brazil.
Renata Guerra-Sá1 Center for Research in Biological Sciences - NUPEB, Federal University of Ouro Preto, 35400-000 Ouro Preto, Brazil.
Maurício Azevedo Batista3 Postgraduate Program in Parasitology, Immunology Laboratory and Genomic Parasites, Federal University of Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
Denise da Silveira-Lemos3 Postgraduate Program in Parasitology, Immunology Laboratory and Genomic Parasites, Federal University of Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
Gustavo Henrique Bianco de Souza1 Center for Research in Biological Sciences - NUPEB, Federal University of Ouro Preto, 35400-000 Ouro Preto, Brazil.
Geraldo Célio Brandão4 Department of Pharmaceutical Sciences - DEFAR, Program Postgraduate Pharmaceutical Sciences (CIPHARMA), School of Pharmacy, Federal University of Ouro Preto, 35400-000 Ouro Preto, Brazil.
Míriam Martins Chaves5 Department of Biochemistry and Immunology, Federal University of Minas Gerais, 31270-901 Belo Horizonte, Brazil.
Daniela Caldeira Costa1 Center for Research in Biological Sciences - NUPEB, Federal University of Ouro Preto, 35400-000 Ouro Preto, Brazil.
Universidade Federal de Ouro Preto · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baccharis trimera, popularly known as "carqueja", is a native South-American plant possessing a high concentration of polyphenolic compounds and therefore high antioxidant potential. Despite the antioxidant potential described for B. trimera, there are no reports concerning the signaling pathways involved in this process. So, the aim of the present study was to assess the influence of B. trimera on the modulation of PKC signaling pathway and to characterize the effect of the nicotinamide adenine dinucleotide phosphate oxidase enzyme (NOX) on the generation of reactive oxygen species in SK Hep-1 cells. SK-Hep 1 cells were treated with B. trimera, quercetin, or rutin and then stimulated or not with PMA/ionomycin and labeled with carboxy H

Indexed as

AntioxidantsBaccharisCell LineHepatocytesHumansIonomycinNADPH OxidasesOxidative StressPhosphorylationPlant PreparationsProtein Kinase CQuercetinReactive Oxygen SpeciesRutinSignal TransductionAntioxidantsIonomycinNADPH Oxidasesneutrophil cytosolic factor 1Plant PreparationsProtein Kinase CQuercetinReactive Oxygen SpeciesRutinBaccharis trimeranicotinamide adenine dinucleotide phosphate oxidasePKCquercetinreactive oxygen speciesrutin

Identifiers

PMID28103717
PMCPMC5384499
OpenAlexW2528644979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.