Evidence map›Paper›PMID 28103713›Full record

ArticleThe American journal of psychiatry2017

Divorce and the Onset of Alcohol Use Disorder: A Swedish Population-Based Longitudinal Cohort and Co-Relative Study.

Kenneth S Kendler, Sara Larsson Lönn, Jessica Salvatore, Jan Sundquist, Kristina Sundquist

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
8.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Acute Alcohol Use and Suicide.JAMA network open · 2025
    Article
  6. Review
  7. Family Genetic-Risk Profiles Associated With Divorce.Clinical psychological science : a journal of the Association for Psychological Science · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Military service and risk of subsequent drug use disorders among Swedish men.Social psychiatry and psychiatric epidemiology · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Separations of romantic relationships are experienced differently by initiators and noninitiators.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kenneth S KendlerFrom the Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Va.; the Department of Psychiatry, Virginia Commonwealth University, Richmond, Va.; the Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Va.; the Center for Primary Health Care Research, Lund University, Malmö, Sweden; and the Department of Psychology, Virginia Commonwealth University, Richmond, Va.
Sara Larsson LönnFrom the Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Va.; the Department of Psychiatry, Virginia Commonwealth University, Richmond, Va.; the Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Va.; the Center for Primary Health Care Research, Lund University, Malmö, Sweden; and the Department of Psychology, Virginia Commonwealth University, Richmond, Va.
Jessica SalvatoreFrom the Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Va.; the Department of Psychiatry, Virginia Commonwealth University, Richmond, Va.; the Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Va.; the Center for Primary Health Care Research, Lund University, Malmö, Sweden; and the Department of Psychology, Virginia Commonwealth University, Richmond, Va.
Jan SundquistFrom the Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Va.; the Department of Psychiatry, Virginia Commonwealth University, Richmond, Va.; the Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Va.; the Center for Primary Health Care Research, Lund University, Malmö, Sweden; and the Department of Psychology, Virginia Commonwealth University, Richmond, Va.
Kristina SundquistFrom the Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Va.; the Department of Psychiatry, Virginia Commonwealth University, Richmond, Va.; the Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Va.; the Center for Primary Health Care Research, Lund University, Malmö, Sweden; and the Department of Psychology, Virginia Commonwealth University, Richmond, Va.
Virginia Commonwealth University · US

Funding

Social, Developmental and Genetic Epidemiology of Alcohol Use DisordersR01AA023534 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENDLER, KENNETH SEEDMAN, SUNDQUIST, KRISTINA · 2015 to 2023
$4.0M
Genetics, Romantic Relationships, and Alcohol Misuse in Emerging AdulthoodK01AA024152 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI SALVATORE, JESSICA E · 2016 to 2020
$741k
NIAAA NIH HHS K01 AA024152NIAAA NIH HHS R01 AA023534
6 · The paper itself

Abstract

objectiveThe purpose of this study was to clarify the magnitude and nature of the relationship between divorce and risk for alcohol use disorder (AUD).

methodIn a population-based Swedish sample of married individuals (N=942,366), the authors examined the association between divorce or widowhood and risk for first registration for AUD. AUD was assessed using medical, criminal, and pharmacy registries.

resultsDivorce was strongly associated with risk for first AUD onset in both men (hazard ratio=5.98, 95% CI=5.65-6.33) and women (hazard ratio=7.29, 95% CI=6.72-7.91). The hazard ratio was estimated for AUD onset given divorce among discordant monozygotic twins to equal 3.45 and 3.62 in men and women, respectively. Divorce was also associated with an AUD recurrence in those with AUD registrations before marriage. Furthermore, widowhood increased risk for AUD in men (hazard ratio=3.85, 95% CI=2.81-5.28) and women (hazard ratio=4.10, 95% CI=2.98-5.64). Among divorced individuals, remarriage was associated with a large decline in AUD in both sexes (men: hazard ratio=0.56, 95% CI=0.52-0.64; women: hazard ratio=0.61, 95% CI=0.55-0.69). Divorce produced a greater increase in first AUD onset in those with a family history of AUD or with prior externalizing behaviors.

conclusionsSpousal loss through divorce or bereavement is associated with a large enduring increased AUD risk. This association likely reflects both causal and noncausal processes. That the AUD status of the spouse alters this association highlights the importance of spouse characteristics for the behavioral health consequences of spousal loss. The pronounced elevation in AUD risk following divorce or widowhood, and the protective effect of remarriage against subsequent AUD, speaks to the profound impact of marriage on problematic alcohol use.

Indexed as

AdultAlcohol-Related DisordersCohort StudiesDivorceFemaleGenetic Predisposition to DiseaseHumansLongitudinal StudiesMaleMarriageProportional Hazards ModelsRegistriesRiskSex FactorsStatistics as TopicSwedenAlcohol AbuseEpidemiology

Identifiers

PMID28103713
PMCPMC5411284
OpenAlexW2572498576

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.