Evidence map›Paper›PMID 28103580›Full record

ArticleOncotarget2017

Biodegradable and biocompatible high elastic chitosan scaffold is cell-friendly both in vitro and in vivo.

Yichuan Pang, An Qin, Xianfeng Lin, Lin Yang, Qiang Wang, Zhengke Wang, Zhi Shan, Shengyun Li, Jiying Wang, Shunwu Fan and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yichuan PangDepartment of Polymer Science and Engineering,MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Zhejiang University, Hangzhou, China.
An QinDepartment of Orthopedic Surgery, Shanghai Key Laboratory of Orthopedic Implants, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xianfeng LinDepartment of Orthopaedics, Sir Shaw Run Run Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Lin YangDepartment of Polymer Science and Engineering,MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Zhejiang University, Hangzhou, China.
Qiang WangDepartment of Orthopaedics, Sir Shaw Run Run Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Zhengke WangDepartment of Polymer Science and Engineering,MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Zhejiang University, Hangzhou, China.
Zhi ShanDepartment of Orthopaedics, Sir Shaw Run Run Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Shengyun LiDepartment of Orthopaedics, Sir Shaw Run Run Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Jiying WangDepartment of Orthopaedics, Sir Shaw Run Run Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Shunwu FanDepartment of Orthopaedics, Sir Shaw Run Run Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Qiaoling HuDepartment of Polymer Science and Engineering,MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Zhejiang University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biodegradable and biocompatible macromolecule chitosan has been favored for a variety of clinical applications. We reported herein the fabrication of a novel chitosan scaffold with high elasticity. This scaffold can be easily compressed and thus enable the insertion of such scaffold into surgical lesions during minimal invasive surgeries. In addition, this novel scaffold can restore its shape when released. We evidenced that this high elastic scaffold has better biocompatibility than traditional chitosan scaffold. Therefore, this new chitosan material might lead to the manufacture of a variety of novel biodegradable biomedical materials and devices.

Indexed as

Biocompatible MaterialsChitosanTissue ScaffoldsAnimalsCell DifferentiationCell LineCell SurvivalElasticityMaterials TestingMesenchymal Stem CellsOsteogenesisRabbitsTissue EngineeringBiocompatible MaterialsChitosanchitosanelastic scaffoldosteogenesistissue engineering

Identifiers

PMID28103580
PMCPMC5482600

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.