ArticlePloS one2017
Significance of Serum Total Oxidant/Antioxidant Status in Patients with Colorectal Cancer.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
72 citing papers in PubMed, 124 citations in OpenAlex.
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- Redox profiling of preovulatory follicular fluid in the donkey is species-specific, and contributes to modulate sperm function.Scientific reports · 2025Article
- Chemical Fingerprinting, Anti-Inflammatory, and Antioxidant Potential of Hydroethanolic Extract ofFood science & nutrition · 2025Article
- Assessment of various etiological factors for oral squamous cell carcinoma in non-habit patients- a cross sectional case control study.BMC oral health · 2025Article
- Preoperative oxidative stress as a biomarker of postoperative complications in colorectal cancer patients.Przeglad gastroenterologiczny · 2025Article
- Total Antioxidant and Oxidative Status as Potential Biomarkers of Alcohol Overdose.International journal of molecular sciences · 2024Article
- The Phytochemical Composition and Antioxidant Activity ofNutrients · 2024Article
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- Field and biochemical evaluation of glyphosate tolerant chickpea (Cicer arietinum L.) mutants developed through induced mutagenesis.BMC plant biology · 2024Article
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- Evaluation of Oxidative Stress, Anti-Oxidant, Vitamins and Co-Factor Elements in The Sera of Gastric Cancer in Iraqi Patients.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- Selenium, Zinc, and Plasma Total Antioxidant Status and the Risk of Colorectal Adenoma and Cancer.Metabolites · 2024Article
- Phytochemical Profile and Antidiabetic, Antioxidant, and Anti-Inflammatory Activities ofAntioxidants (Basel, Switzerland) · 2024Article
- From balance to imbalance: disruption of plasma glutathione concentration in micropapillary thyroid carcinoma.Thyroid research · 2024Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress is involved in a variety of diseases. Prospective studies investigating the relationship between oxidative stress biomarkers and the status and development of colorectal cancer (CRC) are scarce; previous studies have failed to establish a relationship between the serum total oxidant/antioxidant status and CRC. Therefore, we compared the total serum oxidant/antioxidant levels of CRC patients and healthy subjects, and analyzed their clinical significance in the CRC. Fasting blood samples from 132 CRC patients and 64 healthy subjects were collected. Oxidative stress parameters, including total oxidant status (TOS) and total antioxidant status (TAS), were measured, and the oxidative stress index (OSI) was calculated. The TOS and OSI levels increased significantly (P<0.001) and the TAS level significantly decreased (P<0.001) in the CRC group compared to those in the healthy control group. Oxidative stress parameters differed significantly depending on the patient's smoking and drinking status (P<0.05). The preoperative and postoperative levels of TOS, TAS, and OSI did not differ significantly between primary sites (colon/rectum) and clinical stages (P>0.05).However, the levels of TOS, TAS, and OSI were significantly different between patients with no metastasis and those with metastases to two organs (P<0.05) Finally, the parameters are affected by smoking and drinking, and subsequent research should be conducted excluding the relevant influencing factors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.