ArticleAutophagy2017
PARK2-dependent mitophagy induced by acidic postconditioning protects against focal cerebral ischemia and extends the reperfusion window.
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In one paragraph
Article in Autophagy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.
- Neuroprotective Role of Acidosis in Ischemia: Review of the Preclinical Evidence.Molecular neurobiology · 2021Pooled it
- HPC restores mitochondrial homeostasis and ameliorates hypoxic stress through the GSK-3β/β-catenin signaling pathway.Cell death & disease · 2026Article
- Ferroptosis and Its Crosstalk with Other Cell Death Modes in Ischemic Stroke.Current medicinal chemistry · 2026Review
- LncRNA Tug1 Regulates Post-Stroke Microglial Pyroptosis via PINK1/Parkin-Mediated Mitophagy.Inflammation · 2025Article
- Modulation of autophagy by melatonin and its receptors: implications in brain disorders.Acta pharmacologica Sinica · 2025Review
- Acupuncture alleviates hemorrhagic transformation after delayed rt-PA treatment for acute ischemic stroke by regulating the mitophagy-NLRP3 inflammasome pathway.Frontiers in neurology · 2025Article
- Exercise training alleviates neuronal apoptosis and re-establishes mitochondrial quality control after cerebral ischemia by increasing SIRT3 expression.Cell biology and toxicology · 2024Article
- Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.Redox biology · 2024Article
- Inhibition of the AP-1/TFPI2 axis contributes to alleviating cerebral ischemia/reperfusion injury by improving blood-brain barrier integrity.Human cell · 2024Article
- Five percent CONeuroprotection (Chichester, England) · 2024Article
- Regulated cell death in hypoxic-ischaemic encephalopathy: recent development and mechanistic overview.Cell death discovery · 2024Review
- Delayed Chronic Acidic Postconditioning Improves Poststroke Motor Functional Recovery and Brain Tissue Repair by Activating Proton-Sensing TDAG8.Translational stroke research · 2024Article
- Molecular network mechanism in cerebral ischemia-reperfusion rats treated with human urine stem cells.Heliyon · 2024Article
- The Multiple Roles of Autophagy in Neural Function and Diseases.Neuroscience bulletin · 2024Review
- Shared Proteins and Pathways of Cardiovascular and Cognitive Diseases: Relation to Vascular Cognitive Impairment.Journal of proteome research · 2024Article
- The mitochondria as a potential therapeutic target in cerebral I/R injury.Frontiers in neuroscience · 2024Review
- Delayed COCNS neuroscience & therapeutics · 2023Article
- Article
- NCell death discovery · 2023Article
- Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy.Acta pharmacologica Sinica · 2023Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Zhe Shena Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Yanrong Zhenga Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Jiaying Wua Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Ying Chena Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Xiaoli Wua Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Yiting Zhoua Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Yang Yuana Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Shousheng Lua Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Lei Jianga Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Zhenghong Qinb Department of Pharmacology and Laboratory of Aging and Nervous Diseases , Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases, School of Pharmaceutical Science, Soochow University , Suzhou , China.
Zhong Chena Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Weiwei Hua Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Xiangnan Zhanga Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences , Department of Pharmacology , Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University , Hangzhou , China.
Zhejiang University · CNSoochow University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prompt reperfusion after cerebral ischemia is critical for neuronal survival. Any strategies that extend the limited reperfusion window will be of great importance. Acidic postconditioning (APC) is a mild acidosis treatment that involves inhaling CO
Indexed as
Ischemic PostconditioningMitophagyAnimalsBrainBrain IschemiaCarbon DioxideCells, CulturedInfarction, Middle Cerebral ArteryMaleMice, Inbred C57BLMitochondriaNeuronsNeuroprotectionProtein TransportReperfusion InjuryUbiquitin-Protein LigasesCarbon Dioxideparkin proteinUbiquitin-Protein Ligasesacidic postconditioningcerebral ischemiamitophagyneuroprotectionPARK2time window
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.