Evidence map›Paper›PMID 28103039›Full record

ArticleNano letters2017

Single-Walled Carbon Nanotubes: Mimics of Biological Ion Channels.

Hasti Amiri, Kenneth L Shepard, Colin Nuckolls, Raúl Hernández Sánchez

Open access · greenAbstract read
In one paragraph

Article in Nano letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hasti AmiriDepartment of Chemistry and ‡Department of Electrical Engineering, Columbia University , New York, New York 10027, United States.
Kenneth L Shepard
Colin NuckollsDepartment of Chemistry and ‡Department of Electrical Engineering, Columbia University , New York, New York 10027, United States.ORCID 0000-0002-0384-5493
Raúl Hernández SánchezDepartment of Chemistry and ‡Department of Electrical Engineering, Columbia University , New York, New York 10027, United States.
Columbia University · US

Funding

Studies of Riboswitch-Mediated Transcriptional Control Using Single-Molecule FielR01GM107417 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GONZALEZ, RUBEN L, NUCKOLLS, COLIN P · 2014 to 2017
$1.5M
NIGMS NIH HHS R01 GM107417
6 · The paper itself

Abstract

Here we report on the ion conductance through individual, small diameter single-walled carbon nanotubes. We find that they are mimics of ion channels found in natural systems. We explore the factors governing the ion selectivity and permeation through single-walled carbon nanotubes by considering an electrostatic mechanism built around a simplified version of the Gouy-Chapman theory. We find that the single-walled carbon nanotubes preferentially transported cations and that the cation permeability is size-dependent. The ionic conductance increases as the absolute hydration enthalpy decreases for monovalent cations with similar solid-state radii, hydrated radii, and bulk mobility. Charge screening experiments using either the addition of cationic or anionic polymers, divalent metal cations, or changes in pH reveal the enormous impact of the negatively charged carboxylates at the entrance of the single-walled carbon nanotubes. These observations were modeled in the low-to-medium concentration range (0.1-2.0 M) by an electrostatic mechanism that mimics the behavior observed in many biological ion channel-forming proteins. Moreover, multi-ion conduction in the high concentration range (>2.0 M) further reinforces the similarity between single-walled carbon nanotubes and protein ion channels.

Indexed as

CationsIon ChannelsIon TransportNanotubes, CarbonParticle SizePermeabilityPolymersPorosityStatic ElectricityStructure-Activity RelationshipThermodynamicsCationsIon ChannelsNanotubes, CarbonPolymersIon channelmulti-ion conductionnanofluidic devicesingle-walled carbon nanotubes

Identifiers

PMID28103039
PMCPMC5301282
OpenAlexW2576327853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.