Evidence map›Paper›PMID 28102819›Full record

ArticleeLife2017

Rethinking origin licensing.

Stephen P Bell

Abstract readComment
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Regulation of DNA Replication Licensing and Re-Replication by Cdt1.International journal of molecular sciences · 2021
    Review
  6. Article
  7. Article
  8. USP7 Is a Master Regulator of Genome Stability.Frontiers in cell and developmental biology · 2020
    Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Stephen P BellDepartment of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, United States.ORCID 0000-0002-2876-610X

Funding

INITIATION OF DNA REPLICATION OF YEAST CHROMOSOMESR01GM052339 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P. · 1995 to 2019
$5.5M
6 · The paper itself

Abstract

Human cells that lack a subunit in their origin recognition complex are viable, which suggests the existence of alternative mechanisms to initiate DNA replication.

Indexed as

Cell Cycle ProteinsDNA-Binding ProteinsDNA ReplicationHumansMinichromosome Maintenance ProteinsOrigin Recognition ComplexSaccharomyces cerevisiaeXenopus ProteinsCell Cycle ProteinsDNA-Binding ProteinsMinichromosome Maintenance ProteinsOrigin Recognition ComplexXenopus ProteinsCDC6CDT1cell biologyDNA replicationhumanMCM2-7ORC

Identifiers

PMID28102819
PMCPMC5245959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.