Evidence map›Paper›PMID 28102541›Full record

ReviewEuropean journal of immunology2017

TGF-β regulation of encephalitogenic and regulatory T cells in multiple sclerosis.

Priscilla W Lee, Mary E Severin, Amy E Lovett-Racke

Open access · greenAbstract readReview
In one paragraph

Review in European journal of immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Priscilla W LeeDepartment of Microbial Infection and Immunity, Ohio State University, Columbus, OH, USA.
Mary E SeverinDepartment of Microbial Infection and Immunity, Ohio State University, Columbus, OH, USA.
Amy E Lovett-RackeDepartment of Microbial Infection and Immunity, Ohio State University, Columbus, OH, USA.
The Ohio State University · USInstitute of Infection and Immunity · CA

Funding

Molecular Analysis of Genes Uniquely Expressed by Encephalitogenic T CellsR01NS067441 · NINDS · OHIO STATE UNIVERSITY · PI LOVETT-RACKE, AMY E · 2010 to 2014
$1.5M
Role of dysregulated miRNA in Tregs in Multiple SclerosisR21NS078390 · NINDS · OHIO STATE UNIVERSITY · PI LOVETT-RACKE, AMY E · 2012 to 2013
$413k
The Ohio State University Center for Clinical and Translational Science (TL1)TL1TR000091 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2012 to 2013
$384k
NCATS NIH HHS TL1 TR000091NINDS NIH HHS R01 NS067441NINDS NIH HHS R21 NS078390
6 · The paper itself

Abstract

Transforming growth factor beta (TGF-β) is a pleiotropic cytokine that has been shown to influence the differentiation and function of T cells. The role that TGF-β plays in immune-mediated disease, such as multiple sclerosis (MS), has become a major area of investigation since CD4

Indexed as

AnimalsAutoantigensAutoimmunityDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalHumansMiceMultiple SclerosisSignal TransductionT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsTransforming Growth Factor betaAutoantigensTransforming Growth Factor betaExperimental autoimmune encephalomyelitis (EAE)miRNAMultiple sclerosisT cellsTGF-β

Identifiers

PMID28102541
PMCPMC5499671
OpenAlexW2574076923

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.