Evidence map›Paper›PMID 28102523›Full record

ArticleNanoscale research letters2017

The Effect of Superparamagnetic Iron Oxide Nanoparticle Surface Charge on Antigen Cross-Presentation.

Yongbin Mou, Yun Xing, Hongyan Ren, Zhihua Cui, Yu Zhang, Guangjie Yu, Walter J Urba, Qingang Hu, Hongming Hu

Open access · goldAbstract read
In one paragraph

Article in Nanoscale research letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Review
  3. Metallic nanomedicine in cancer immunotherapy.Acta pharmaceutica Sinica. B · 2025
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  8. Biomaterials Facilitating Dendritic Cell-Mediated Cancer Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  9. Review
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  11. Article
  12. Self-adjuvanting cancer nanovaccines.Journal of nanobiotechnology · 2022
    Review
  13. Review
  14. Effect of physicochemical properties onActa pharmaceutica Sinica. B · 2021
    Review
  15. Review
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Yongbin MouNanjing Stomatological Hospital, Medical School of Nanjing University, 30#, Zhongyang Road, Nanjing, 210008, People's Republic of China.
Yun XingLaboratory of Cancer Immunobiology, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center, Portland, OR, USA.
Hongyan RenLaboratory of Cancer Immunobiology, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center, Portland, OR, USA.
Zhihua CuiLaboratory of Cancer Immunobiology, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center, Portland, OR, USA.
Yu ZhangState Key Laboratory of Molecule and Bimolecular Electronics, Jiangsu Provincial Laboratory for Biomaterials and Devices, Southeast University, Nanjing, People's Republic of China.
Guangjie YuLaboratory of Cancer Immunobiology, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center, Portland, OR, USA.
Walter J UrbaCancer Research, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center, 4805 NE Glisan Street, Portland, OR, 97213, USA.
Qingang HuNanjing Stomatological Hospital, Medical School of Nanjing University, 30#, Zhongyang Road, Nanjing, 210008, People's Republic of China. qghu@nju.edu.cn.ORCID http://orcid.org/0000-0003-3904-0563
Hongming HuLaboratory of Cancer Immunobiology, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center, Portland, OR, USA. hhu@providence.org.
Providence Portland Medical Center · USChina Pharmaceutical University · CNNanjing Medical University · CNSoutheast University · CN

Funding

Aluminum Oxide Nanoparticles Conjugated to Antigens Potently Induce Tumor SpecifiU43CA165048 · NCI · UBIVAC, LLC · PI HILTON, TRACI LEIGH · 2013 to 2014
$289k
NCI NIH HHS U43 CA165048
6 · The paper itself

Abstract

Magnetic nanoparticles (NPs) of superparamagnetic iron oxide (SPIO) have been explored for different kinds of applications in biomedicine, mechanics, and information. Here, we explored the synthetic SPIO NPs as an adjuvant on antigen cross-presentation ability by enhancing the intracellular delivery of antigens into antigen presenting cells (APCs). Particles with different chemical modifications and surface charges were used to study the mechanism of action of antigen delivery. Specifically, two types of magnetic NPs, γFe

Indexed as

AdjuvantAntigen cross-presentationDendritic cellsSuperparamagnetic iron oxide

Identifiers

PMID28102523
PMCPMC5247387
OpenAlexW2578731703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.