Evidence map›Paper›PMID 28102512›Full record

ReviewImmunologic research2017

Anti-phospholipid syndrome associated with schizophrenia description of five patients and review of the literature.

Pikman Regina, Rotman Pnina, Aiman Natur, Levy Yair

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Autoantibodies and Inflammation in Schizophrenia.Psychiatry and clinical neurosciences · 2025
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pikman ReginaDepartment of Medicine E, Meir Medical Center, 44261, Kfar-Saba, Israel.
Rotman PninaDepartment of Medicine E, Meir Medical Center, 44261, Kfar-Saba, Israel.
Aiman NaturDepartment of Medicine E, Meir Medical Center, 44261, Kfar-Saba, Israel.
Levy YairDepartment of Medicine E, Meir Medical Center, 44261, Kfar-Saba, Israel. levy.yair@clalit.org.il.
Meir Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-phospholipid syndrome is an autoimmune disorder characterized by anti-phospholipid antibodies, arterial and venous thrombosis, pregnancy morbidity, and various neurological manifestations including psychiatric disorders. Higher incidence of various autoimmune disorders was found in schizophrenia. In addition, an association between the presence of anti-phospholipid antibodies and schizophrenia or psychosis was previously described, mainly as case reports. Although initially believed to be a result of neuroleptic treatment, the reasons for this association remain obscure. Several theories on the etiologic basis of schizophrenia that may explain this association were proposed including an immune basis of schizophrenia and a genetic locus of the disease in the human leukocyte antigens area. Herein, we present a series of five patients diagnosed with both schizophrenia and anti-phospholipid syndrome and their characteristics along with a comprehensive review of the current available literature on the subject in an attempt to deepen our understanding of these disorders and their pathogenesis.

Indexed as

AdultAntiphospholipid SyndromeAutoantibodiesAutoimmunityFemaleGenetic Association StudiesHLA AntigensHumansMaleMiddle AgedPsychotic DisordersSchizophreniaAutoantibodiesHLA AntigensAnti-cardiolipinAnti-phospholipid syndromeNeurological manifestationSchizophrenia

Identifiers

PMID28102512
OpenAlexW2576324094

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.