Evidence map›Paper›PMID 28102324›Full record

ArticleScientific reports2017

Antiproliferative and Apoptosis-inducing Effect of exo-Protoporphyrin IX based Sonodynamic Therapy on Human Oral Squamous Cell Carcinoma.

Yanhong Lv, Jinhua Zheng, Qi Zhou, Limin Jia, Chunying Wang, Nian Liu, Hong Zhao, Hang Ji, Baoxin Li, Wenwu Cao

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Emerging Sonodynamic Therapy-Based Nanomedicines for Cancer Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  7. Review
  8. Effects of CuRSC advances · 2022
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yanhong LvDepartment of Anatomy, Harbin Medical University, Harbin, 150086, China.
Jinhua ZhengDepartment of Anatomy, Harbin Medical University, Harbin, 150086, China.
Qi ZhouCondensed Matter Science and Technology Institute, Harbin Institute of Technology, Harbin, 150080, China.
Limin JiaDepartment of Anatomy, Harbin Medical University, Harbin, 150086, China.
Chunying WangCondensed Matter Science and Technology Institute, Harbin Institute of Technology, Harbin, 150080, China.
Nian LiuDepartment of Anatomy, Harbin Medical University, Harbin, 150086, China.
Hong ZhaoDepartment of Anatomy, Harbin Medical University, Harbin, 150086, China.
Hang JiDepartment of Anatomy, Harbin Medical University, Harbin, 150086, China.
Baoxin LiDepartment of Pharmacology, Harbin Medical University, Harbin, 150086, China.
Wenwu CaoCondensed Matter Science and Technology Institute, Harbin Institute of Technology, Harbin, 150080, China.
Harbin Medical University · CNHarbin Institute of Technology · CNPennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sonodynamic therapy (SDT) is an innovative modality for cancer treatment. But the biological effect of SDT on oral squamous cell carcinoma has not been studied. Our previous study has shown that endo-Protoporphyrin IX based SDT (ALA-SDT) could induce apoptosis in human tongue squamous carcinoma SAS cells through mitochondrial pathway. Herein, we investigated the effect of exo- Protoporphyrin based SDT (PpIX-SDT) on SAS cells in vitro and in vivo. We demonstrated that PpIX-SDT increased the ratio of cells in the G

Indexed as

AnimalsApoptosisCarcinoma, Squamous CellCell SurvivalHumansMice, Inbred BALB CMice, NudeModels, BiologicalMouth NeoplasmsNeoplasm TransplantationPhotosensitizing AgentsProtoporphyrinsSonicationTreatment OutcomeTumor Cells, CulturedPhotosensitizing Agentsprotoporphyrin IXProtoporphyrins

Identifiers

PMID28102324
PMCPMC5244424
OpenAlexW2574972041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.