Evidence map›Paper›PMID 28102227›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2018

Singular Location and Signaling Profile of Adenosine A

Estefanía Moreno, Anna Chiarlone, Mireia Medrano, Mar Puigdellívol, Lucka Bibic, Lesley A Howell, Eva Resel, Nagore Puente, María J Casarejos, Juan Perucho and 13 more

Open access · hybridAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 65 citations in OpenAlex.

  1. Trial
  2. Article
  3. Genetic Tools in Rodents to Study Cannabinoid Functions.Current topics in behavioral neurosciences · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Neuronal and astrocytic CB1R signaling differentially modulates goal-directed behavior and working memory by distinct temporal mechanisms.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  8. Article
  9. Striatopallidal adenosine ANeuropharmacology · 2023
    Review
  10. Endocannabinoid-Binding Receptors as Drug Targets.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  11. Article
  12. Allosteric Modulation of Adenosine AInternational journal of molecular sciences · 2022
    Review
  13. Review
  14. Review
  15. Review
  16. Identification of BiP as a CBThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  17. Article
  18. Article
  19. Cannabis for Restless Legs Syndrome.Advances in experimental medicine and biology · 2021
    Review
  20. Neurobiology of cannabinoid receptor signaling
.Dialogues in clinical neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 7 institutions in 3 countries.

Estefanía MorenoCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Anna ChiarloneCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Mireia MedranoCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Mar PuigdellívolSchool of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, UK.
Lucka BibicSchool of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, UK.
Lesley A HowellSchool of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, UK.
Eva ReselCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Nagore PuenteDepartment of Neurosciences, University of the Basque Country UPV/EHU, Leioa, Spain.
María J CasarejosInstituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain.
Juan PeruchoInstituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain.
Joaquín BottaSchool of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, UK.
Nuria SuelvesCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Francisco CiruelaPharmacology Unit, Department of Pathology and Experimental Therapeutics, IDIBELL, and Neuroscience Institute, Barcelona University, Barcelona, Spain.
Silvia GinésCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Ismael Galve-RoperhCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Vicent CasadóCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Pedro GrandesDepartment of Neurosciences, University of the Basque Country UPV/EHU, Leioa, Spain.
Beat LutzInstitute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Krisztina MonoryInstitute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Enric I CanelaCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.ORCID 0000-0003-4992-7440
Carmen LluísCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Peter J McCormickCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Manuel GuzmánCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Instituto de Salud Carlos III · ESUniversity of East Anglia · GBUniversidad Complutense de Madrid · ESInstituto Ramón y Cajal de Investigación Sanitaria · ESJohannes Gutenberg University Mainz · DEUniversity of the Basque Country · ESInstitut d'Investigació Biomédica de Bellvitge · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dorsal striatum is a key node for many neurobiological processes such as motor activity, cognitive functions, and affective processes. The proper functioning of striatal neurons relies critically on metabotropic receptors. Specifically, the main adenosine and endocannabinoid receptors present in the striatum, ie, adenosine A

Indexed as

Protein Structure, QuaternarySignal TransductionAnimalsCorpus StriatumHumansHuntington DiseaseMiceNeural PathwaysProtein SubunitsReceptor, Adenosine A2AReceptor, Cannabinoid, CB1Protein SubunitsReceptor, Adenosine A2AReceptor, Cannabinoid, CB1

Identifiers

PMID28102227
PMCPMC5854787
OpenAlexW2572114287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.