Evidence map›Paper›PMID 28101734›Full record

ReviewGlycoconjugate journal2017

Chondroitin sulfates and their binding molecules in the central nervous system.

L Djerbal, H Lortat-Jacob, Jcf Kwok

Abstract readReview
In one paragraph

Review in Glycoconjugate journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Critical Periods and Beyond: Dynamic Functions of Perineuronal Nets in Cognition, Development, and Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
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  16. Article
  17. Review
  18. Article
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  20. Polysaccharide functionalization reduces lipid vesicle stiffness.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

L DjerbalInstitut de Biologie Structurale, University Grenoble Alpes, CNRS, CEA, F-38027, Grenoble, France.
H Lortat-JacobInstitut de Biologie Structurale, University Grenoble Alpes, CNRS, CEA, F-38027, Grenoble, France. hugues.lortat-jacob@ibs.fr.
Jcf KwokSchool of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK. j.kwok@leeds.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in the central nervous system (CNS) matrix. Its sulfation and epimerization patterns give rise to different forms of CS, which enables it to interact specifically and with a significant affinity with various signalling molecules in the matrix including growth factors, receptors and guidance molecules. These interactions control numerous biological and pathological processes, during development and in adulthood. In this review, we describe the specific interactions of different families of proteins involved in various physiological and cognitive mechanisms with CSs in CNS matrix. A better understanding of these interactions could promote a development of inhibitors to treat neurodegenerative diseases.

Indexed as

AnimalsCarbohydrate ConformationCarrier ProteinsCentral Nervous SystemChondroitin SulfatesCytokinesExtracellular MatrixExtracellular Matrix ProteinsHumansIntercellular Signaling Peptides and ProteinsMidkineNeural Cell Adhesion MoleculesNeuronsProtein BindingProteoglycansReceptor-Like Protein Tyrosine PhosphatasesCarrier ProteinsChondroitin SulfatesCytokinesExtracellular Matrix ProteinsIntercellular Signaling Peptides and ProteinsMidkineNeural Cell Adhesion MoleculespleiotrophinProteoglycansReceptor-Like Protein Tyrosine PhosphatasesCentral nervous systemChondroitin sulfateGlycosaminoglycansPerineuronal netsPlasticityProtein-glycosaminoglycan interactionsProteoglycans

Identifiers

PMID28101734
PMCPMC5487772

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.