Evidence map›Paper›PMID 28101721›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2017

Quantitative Assessment of Visceral Obesity and Postoperative Colon Cancer Outcomes.

Oluwatobi O Ozoya, Erin M Siegel, Thejal Srikumar, Amanda M Bloomer, Amanda DeRenzis, David Shibata

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02328677 (ColoCare Transdisciplinary Research in Colorectal Cancer Prognosis), which is not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02328677 recruitingnot on this map

ColoCare Transdisciplinary Research in Colorectal Cancer Prognosis

TypeobservationalSponsorUniversity of UtahRan2007 to 2030Enrolled5,000ConditionsColorectal Cancer
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  16. Body Composition Predictors of Adverse Postoperative Events in Patients Undergoing Surgery for Long Bone Metastases.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Oluwatobi O OzoyaDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA.
Erin M SiegelDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA.
Thejal SrikumarDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA.
Amanda M BloomerDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA.
Amanda DeRenzisDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA.
David ShibataDepartment of Surgery, University of Tennessee Health Science Center, 910 Madison Avenue, Room 203, Memphis, TN, 38163, USA. dshibata@uthsc.edu.ORCID 0000-0002-5670-423X
Moffitt Cancer Center · USUniversity of South Florida · USUniversity of Tennessee Health Science Center · US

Funding

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare StudyU01CA206110 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jane C. Figueiredo, Christopher I Li · 2016 to 2026
$18.6M
Metabolomic Strategies for Discovery and Validation of Biomarkers of Colorectal Cancer RecurrenceR01CA207371 · NCI · UNIVERSITY OF UTAH · PI LI, CHRISTOPHER I, ULRICH, CORNELIA M · 2017 to 2022
$3.9M
NCI NIH HHS R01 CA207371NCI NIH HHS U01 CA206110
6 · The paper itself

Abstract

backgroundQuantitative computed tomography (CT) assessment of visceral adiposity may be superior to body mass index (BMI) as a predictor of surgical morbidity. We sought to examine the association of CT measures of obesity and BMI with short-term postoperative outcomes in colon cancer patients.

methodsIn this retrospective study, 110 patients treated with colectomy for stage I-III colon cancer were classified as obese or non-obese by preoperative CT-based measures of adiposity or BMI [obese: BMI ≥ 30 kg/m

resultsObese patients, by V/S and VFA but not BMI, were more likely to be male and have preexisting hypertension and diabetes. The overall complication rate was 25.5%, and there were no mortalities. Obese patients by VFA (with a trend for V/S but not BMI) were more likely to develop postoperative complications as compared to patients classified as non-obese: VFA (30.5 vs.10.7%, p = 0.03), V/S (29.2 vs. 9.5%, p = 0.05), and BMI (32.4 vs. 21.9%, p = 0.23).

conclusionsElevated visceral obesity quantified by CT is associated with the presence of key metabolic comorbidities and increased postoperative morbidity and may be superior to BMI for risk stratification.

Indexed as

AgedBody Mass IndexColectomyColonic NeoplasmsComorbidityFemaleHumansIntra-Abdominal FatMaleMiddle AgedObesity, AbdominalRetrospective StudiesRisk AssessmentRisk FactorsSubcutaneous FatTomography, X-Ray ComputedColon cancerComputed tomographySurgical complicationVisceral obesity

Identifiers

PMID28101721
PMCPMC5560865
OpenAlexW2576030891

What OpenQuestion holds

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LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.