ArticleInternational journal of legal medicine2017
Forensic parameters of 19 X-STR polymorphisms in two Chinese populations.
Article in International journal of legal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Validation and forensic application of a new 36 X-chromosomal short tandem repeat loci multiplex system.Forensic sciences research · 2025Article
- A novel 193-plex MPS panel integrating STRs and SNPs highlights the application value of forensic genetics in individual identification and paternity testing.Human genetics · 2024Article
- Genetic Polymorphisms and Forensic Parameters of Thirteen X-Chromosome Markers in the Iraqi Kurdish Population.Journal of nucleic acids · 2024Article
- A forensic population database of autosomal STR and X-STR markers in the Qiang ethnic minority of China.Heliyon · 2023Article
- Genetic portrait and phylogenetic analysis of an Aksu Uyghur population based on the 19 X-STR system.International journal of legal medicine · 2019Article
- Genetic structure and polymorphisms of Gelao ethnicity residing in southwest china revealed by X-chromosomal genetic markers.Scientific reports · 2018Article
- X-chromosomal STR-based genetic structure of Sichuan Tibetan minority ethnicity group and its relationships to various groups.International journal of legal medicine · 2018Article
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8 authors.
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Abstract
Application of X-STRs as complements of autosomal STR application in the forensic genetics has become a tendency for kinship testing, especially in deficiency paternity cases. Recently, a novel kit of 19 X-STR loci was developed, which permitted the analysis of 19 STR in the same PCR reaction, and these markers can be clustered into seven groups for the physical linkage. The objective of this study was to evaluate the allele and haplotype diversity of 19 X-STR loci in the Uygur (n = 220) and Tibetan nationality (n = 270) and to estimate the usefulness for complex kinship analysis. In the Tibetan and Uygur populations, a total of alleles of all loci were 188 and 212, with the allele frequencies ranged from 0.0037 to 0.5593 and from 0.0045 to 0.5409, respectively. Compared with previous studies, DXS10135 was the most polymorphic locus in the two population groups, whereas the least variant locus was DXS10164 in the Uygur population and DXS7423 in the Tibetan nationality. Haplotype diversity obtained in this investigation was greater than 0.9 across all LGs. This study indicated the new kit could be used as a supplementary tool in kinship testing in China. In addition, the data sets can be used as supplementary national X-STR references to enlarge the database.
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