ArticleEuropean thyroid journal2016
Thyroid Function and High-Sensitivity C-Reactive Protein in Cross-Sectional Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil): Effect of Adiposity and Insulin Resistance.
Article in European thyroid journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Study of Thyroid Function Tests and Inflammatory Markers (White Blood Cell Count and High-sensitivity C-reactive Protein) in Prediabetic Patients at Tertiary Care Center.Annals of African medicine · 2026Article
- C-Reactive Protein: Pathophysiology, Diagnosis, False Test Results and a Novel Diagnostic Algorithm for Clinicians.Diseases (Basel, Switzerland) · 2023Review
- Causal Association of Thyroid Signaling with C-Reactive Protein: A Bidirectional Mendelian Randomization.Computational and mathematical methods in medicine · 2022Article
- Four-year adiposity change and remission of hypertension: an observational evaluation from the Longitudinal Study of Adult Health (ELSA-Brasil).Journal of human hypertension · 2020Article
- The role of thyroid hormone in metabolism and metabolic syndrome.Therapeutic advances in endocrinology and metabolism · 2020Review
- FABP4 levels in hypothyroidism and its relationship with subclinical atherosclerosisTurkish journal of medical sciences · 2019Article
- High TSH Level within Normal Range Is Associated with Obesity, Dyslipidemia, Hypertension, Inflammation, Hypercoagulability, and the Metabolic Syndrome: A Novel Cardiometabolic Marker.Journal of clinical medicine · 2019Article
- Thyroid disorders in Brazil: the contribution of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Article
- Levothyroxine Replacement Alleviates Thyroid Destruction in Hypothyroid Patients With Autoimmune Thyroiditis: Evidence From a Thyroid MRI Study.Frontiers in endocrinology · 2019Article
- Metabolic Syndrome, Thyroid Function and Autoimmunity - The PORMETS Study.Endocrine, metabolic & immune disorders drug targets · 2019Article
- Low total and free triiodothyronine levels are associated with insulin resistance in non-diabetic individuals.Scientific reports · 2018Article
- EVALUATION OF THE ASSOCIATION OF PLASMA PENTRAXIN-3 LEVELS WITH CAROTID INTIMA-MEDIA THICKNESS AND HIGH-SENSITIVE CRP IN PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSubclinical hypothyroidism (SCH) is associated with an increased cardiovascular risk, but little information is available about its association with high-sensitivity C-reactive protein (hs-CRP).
objectivesThis study aims to analyze the association between SCH and hs-CRP using baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
methodsThe study has a cross-sectional design. We included subjects with normal thyroid function (thyroid-stimulating hormone, TSH, 0.4-4.0 μIU/ml and normal free thyroxine, fT
resultsWe included 12,284 subjects with a median age of 50 years (interquartile range = 45-57); 6,408 (52.2%) were female, 11,589 (94.3%) were euthyroid, and 695 (5.7%) had SCH. Bivariate analyses of participants stratified into quintiles of TSH revealed differences according to hs-CRP but not the Framingham risk score. The fifth quintile of TSH was not associated with elevated hs-CRP, odds ratio = 1.11 (95% confidence interval = 0.98-1.26), p = 0.102, in a fully adjusted logistic model, also consistent with the linear model (β = 0.024, p = 0.145).
conclusionsTSH is not associated with hs-CRP. Obesity and insulin resistance are very important confounders in the study of the association between SCH and hs-CRP.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.