Evidence map›Paper›PMID 28101428›Full record

ArticleBiomedical optics express2017

Wide field and highly sensitive angiography based on optical coherence tomography with akinetic swept source.

Jingjiang Xu, Shaozhen Song, Wei Wei, Ruikang K Wang

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
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  10. Review
  11. Cerebral edema detectionNeurophotonics · 2019
    Article
  12. A Practical Method for Creating Targeted Focal Ischemic Stroke in the Cortex of Nonhuman PrimatesAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2019
    Article
  13. Article
  14. Article
  15. Optical coherence tomography angiography.Progress in retinal and eye research · 2018
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Repeatability of vessel density measurement in human skin by OCT-based microangiography.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jingjiang XuUniversity of Washington, Department of Bioengineering, Seattle, Washington 98195, USA.
Shaozhen SongUniversity of Washington, Department of Bioengineering, Seattle, Washington 98195, USA.
Wei WeiUniversity of Washington, Department of Bioengineering, Seattle, Washington 98195, USA.
Ruikang K WangUniversity of Washington, Department of Bioengineering, Seattle, Washington 98195, USA.
University of Washington · US

Funding

OPTICAL MICROANGIOGRAHY OF CEREBROVASCULAR PERFUSIONR01HL093140 · NHLBI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2008 to 2017
$4.2M
NON-INVASIVE REAL-TIME LABEL-FREE 3D IMAGING OF RETINAL MICROCIRCULATIONR01EY024158 · NEI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2014 to 2017
$1.7M
NEI NIH HHS R01 EY024158NHLBI NIH HHS R01 HL093140
6 · The paper itself

Abstract

Wide-field vascular visualization in bulk tissue that is of uneven surface is challenging due to the relatively short ranging distance and significant sensitivity fall-off for most current optical coherence tomography angiography (OCTA) systems. We report a long ranging and ultra-wide-field OCTA (UW-OCTA) system based on an akinetic swept laser. The narrow instantaneous linewidth of the swept source with its high phase stability, combined with high-speed detection in the system enable us to achieve long ranging (up to 46 mm) and almost negligible system sensitivity fall-off. To illustrate these advantages, we compare the basic system performances between conventional spectral domain OCTA and UW-OCTA systems and their functional imaging of microvascular networks in living tissues. In addition, we show that the UW-OCTA is capable of different depth-ranging of cerebral blood flow within entire brain in mice, and providing unprecedented blood perfusion map of human finger in

Indexed as

(110.4500) Optical coherence tomography(140.3600) Lasers, tunable(170.0110) Imaging systems(170.2655) Functional monitoring and imaging(170.3880) Medical and biological imaging

Identifiers

PMID28101428
PMCPMC5231310
OpenAlexW2562281037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.