Evidence map›Paper›PMID 28101420›Full record

ArticleBiomedical optics express2017

Compact diode laser source for multiphoton biological imaging.

Robert D Niederriter, Baris N Ozbay, Gregory L Futia, Emily A Gibson, Juliet T Gopinath

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert D NiederriterDepartment of Physics, University of Colorado, 390 UCB, Boulder, CO 80309-0390, USA.
Baris N OzbayDepartment of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, Mail Stop 8607, 12700 East 19th Ave, Aurora, CO 80045, USA.
Gregory L FutiaDepartment of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, Mail Stop 8607, 12700 East 19th Ave, Aurora, CO 80045, USA.
Emily A GibsonDepartment of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, Mail Stop 8607, 12700 East 19th Ave, Aurora, CO 80045, USA.
Juliet T GopinathDepartment of Physics, University of Colorado, 390 UCB, Boulder, CO 80309-0390, USA; Department of Electrical, Computer, and Energy Engineering, University of Colorado, 425 UCB, Boulder, CO 80309-0425, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We demonstrate a compact, pulsed diode laser source suitable for multiphoton microscopy of biological samples. The center wavelength is 976 nm, near the peak of the two-photon cross section of common fluorescent markers such as genetically encoded green and yellow fluorescent proteins. The laser repetition rate is electrically tunable between 66.67 kHz and 10 MHz, with 2.3 ps pulse duration and peak powers >1 kW. The laser components are fiber-coupled and scalable to a compact package. We demonstrate >600 μm depth penetration in brain tissue, limited by laser power.

Indexed as

(140.3538) Lasers, pulsed(140.5960) Semiconductor lasers(180.2520) Fluorescence microscopy(180.4315) Nonlinear microscopy

Identifiers

PMID28101420
PMCPMC5231301

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.