ArticleBiomedical optics express2017
Visualization of micro-capillaries using optical coherence tomography angiography with and without adaptive optics.
Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Article
- Wide-field choriocapillaris mapping with 3.4 MHz adaptive optics-optical coherence tomography angiography.Biomedical optics express · 2025Article
- Advances in OCT Angiography.Translational vision science & technology · 2025Review
- Review
- Imaging the eye as a window to brain health: frontier approaches and future directions.Journal of neuroinflammation · 2024Review
- Spatially resolved imaging of human macular capillaries using adaptive optics-enhanced optical coherence tomography angiography.Scientific reports · 2024Article
- Detection of capillary abnormalities in early diabetic retinopathy using scanning laser ophthalmoscopy and optical coherence tomography combined with adaptive optics.Scientific reports · 2024Article
- Multifunctional adaptive optics optical coherence tomography allows cellular scale reflectometry, polarimetry, and angiography in the living human eye.Biomedical optics express · 2024Article
- Twenty-five years of clinical applications using adaptive optics ophthalmoscopy [Invited].Biomedical optics express · 2023Review
- Ultrahigh-speed multimodal adaptive optics system for microscopic structural and functional imaging of the human retina.Biomedical optics express · 2022Article
- Multi-modal and multi-scale clinical retinal imaging system with pupil and retinal tracking.Scientific reports · 2022Article
- Blood vessel tail artifacts suppression in optical coherence tomography angiography.Neurophotonics · 2022Article
- DPSF: a Novel Dual-Parametric Sigmoid Function for Optical Coherence Tomography Image Enhancement.Medical & biological engineering & computing · 2022Article
- Spatial-Temporal Speckle Variance in the En-Face View as a Contrast for Optical Coherence Tomography Angiography (OCTA).Sensors (Basel, Switzerland) · 2022Article
- Towards standardizing retinal optical coherence tomography angiography: a review.Light, science & applications · 2022Review
- Article
- Assessment of Detailed Photoreceptor Structure and Retinal Sensitivity in Diabetic Macular Ischemia Using Adaptive Optics-OCT and Microperimetry.Investigative ophthalmology & visual science · 2021Article
- Comparison of retinal vessel diameter measurements from swept-source OCT angiography and adaptive optics ophthalmoscope.The British journal of ophthalmology · 2021Article
- Artifacts and artifact removal in optical coherence tomographic angiography.Quantitative imaging in medicine and surgery · 2021Review
- Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this work is to investigate the benefits of adaptive optics (AO) technology for optical coherence tomography angiography (OCTA). OCTA has shown great potential in non-invasively enhancing the contrast of vessels and small capillaries. Especially the capability of the technique to visualize capillaries with a lateral extension that is below the transverse resolution of the system opens unique opportunities in diagnosing retinal vascular diseases. However, there are some limitations of this technology such as shadowing and projection artifacts caused by overlying vasculature or the inability to determine the true extension of a vessel. Thus, the evaluation of the vascular structure and density based on OCTA alone can be misleading. In this paper we compare the performance of AO-OCT, AO-OCTA and OCTA for imaging retinal vasculature. The improved transverse resolution and the reduced depth of focus of AO-OCT and AO-OCTA greatly reduce shadowing artifacts allowing for a better differentiation and segmentation of different vasculature layers of the inner retina. The comparison is done on images recorded in healthy volunteers and in diabetic patients with distinct pathologies of the retinal microvasculature.
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Registered trials
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