Evidence map›Paper›PMID 28101408›Full record

ArticleBiomedical optics express2017

Dmitry Sonin, Garry Papayan, Evgeniia Pochkaeva, Svetlana Chefu, Sarkis Minasian, Dmitry Kurapeev, Jarle Vaage, Nickolay Petrishchev, Michael Galagudza

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Dmitry SoninCenter for Laser Medicine, Department of Pathophysiology, First I.P. Pavlov Federal Medical University of St. Petersburg, Lev Tolstoy Str. 6/8, 197022, St. Petersburg, Russia; Institute of Experimental Medicine, Federal Almazov Medical Research Centre, Akkuratova Str. 2, 197341, St. Petersburg, Russia; ITMO University, Kronverksky Avenue 49, 197101 St. Petersburg, Russia.
Garry PapayanCenter for Laser Medicine, Department of Pathophysiology, First I.P. Pavlov Federal Medical University of St. Petersburg, Lev Tolstoy Str. 6/8, 197022, St. Petersburg, Russia; Institute of Experimental Medicine, Federal Almazov Medical Research Centre, Akkuratova Str. 2, 197341, St. Petersburg, Russia; ITMO University, Kronverksky Avenue 49, 197101 St. Petersburg, Russia.
Evgeniia PochkaevaInstitute of Experimental Medicine, Federal Almazov Medical Research Centre, Akkuratova Str. 2, 197341, St. Petersburg, Russia.
Svetlana ChefuCenter for Laser Medicine, Department of Pathophysiology, First I.P. Pavlov Federal Medical University of St. Petersburg, Lev Tolstoy Str. 6/8, 197022, St. Petersburg, Russia; Institute of Experimental Medicine, Federal Almazov Medical Research Centre, Akkuratova Str. 2, 197341, St. Petersburg, Russia.
Sarkis MinasianCenter for Laser Medicine, Department of Pathophysiology, First I.P. Pavlov Federal Medical University of St. Petersburg, Lev Tolstoy Str. 6/8, 197022, St. Petersburg, Russia; Institute of Experimental Medicine, Federal Almazov Medical Research Centre, Akkuratova Str. 2, 197341, St. Petersburg, Russia; ITMO University, Kronverksky Avenue 49, 197101 St. Petersburg, Russia.
Dmitry KurapeevCenter for Laser Medicine, Department of Pathophysiology, First I.P. Pavlov Federal Medical University of St. Petersburg, Lev Tolstoy Str. 6/8, 197022, St. Petersburg, Russia.
Jarle VaageITMO University, Kronverksky Avenue 49, 197101 St. Petersburg, Russia; Institute of Clinical Medicine, University of Oslo and Department of Emergency and Intensive Care Medicine, Oslo University Hospital, Postboks 1171, Blindern, 0318 Oslo, Norway.
Nickolay PetrishchevCenter for Laser Medicine, Department of Pathophysiology, First I.P. Pavlov Federal Medical University of St. Petersburg, Lev Tolstoy Str. 6/8, 197022, St. Petersburg, Russia; Institute of Experimental Medicine, Federal Almazov Medical Research Centre, Akkuratova Str. 2, 197341, St. Petersburg, Russia; ITMO University, Kronverksky Avenue 49, 197101 St. Petersburg, Russia.
Michael GalagudzaCenter for Laser Medicine, Department of Pathophysiology, First I.P. Pavlov Federal Medical University of St. Petersburg, Lev Tolstoy Str. 6/8, 197022, St. Petersburg, Russia; Institute of Experimental Medicine, Federal Almazov Medical Research Centre, Akkuratova Str. 2, 197341, St. Petersburg, Russia; ITMO University, Kronverksky Avenue 49, 197101 St. Petersburg, Russia.
Institute of Experimental Medicine · RUITMO University · RUFederal Almazov North-West Medical Research Centre · RUFirst Pavlov State Medical University of St. Petersburg · RUUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fluorophore indocyanine green accumulates in areas of ischemia-reperfusion injury due to an increase in vascular permeability and extravasation of the dye. The aim of the study was to validate an indocyanine green-based technique of in vivo visualization of myocardial infarction. A further aim was to quantify infarct size ex vivo and compare this technique with the standard triphenyltetrazolium chloride staining. Wistar rats were subjected to regional myocardial ischemia (30 minutes) followed by reperfusion (n = 7). Indocyanine green (0.25 mg/mL in 1 mL of normal saline) was infused intravenously for 10 minutes starting from the 25th minute of ischemia. Video registration in the near-infrared fluorescence was performed. Epicardial fluorescence of indocyanine green corresponded to the injured area after 30 minutes of reperfusion. Infarct size was similar when determined ex vivo using traditional triphenyltetrazolium chloride assay and indocyanine green fluorescent labeling. Intravital visualization of irreversible injury can be done directly by fluorescence on the surface of the heart. This technique may also be an alternative for ex vivo measurements of infarct size.

Indexed as

(110.3080) Infrared imaging(170.3880) Medical and biological imaging(300.2530) Fluorescence, laser-induced

Identifiers

PMID28101408
PMCPMC5231288
OpenAlexW2560165452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.