ReviewThe World Allergy Organization journal2017
Is allergic sensitization relevant in severe asthma? Which allergens may be culprit?
Review in The World Allergy Organization journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and risk factors for asthma in East Africa: a systematic review and meta-analysis.BMC pediatrics · 2026Pooled it
- Bronchodilator response is linked with uncontrolled moderate-to-severe childhood asthma and elevated IL-4 and IL-13.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Article
- Trends of aeroallergen sensitization among children with respiratory allergy in Southern Thailand.Asia Pacific allergy · 2024Article
- Fungi-sensitized individuals have unique profiles where Alt a 1 dominates promoting response to grass, ragweed and cat allergens.Frontiers in allergy · 2024Article
- Phenotypes and Endotypes in Asthma.Advances in experimental medicine and biology · 2023Article
- Specific IgE Response and Omalizumab Responsiveness in Severe Allergic Asthma.Journal of asthma and allergy · 2023Article
- Proteinase-activated receptor-2 antagonist C391 inhibits Alternaria-induced airway epithelial signalling and asthma indicators in acute exposure mouse models.British journal of pharmacology · 2022Article
- Different Phenotypes in Asthma: Clinical Findings and Experimental Animal Models.Clinical reviews in allergy & immunology · 2022Review
- Review
- Article
- Predicting Treatment Outcomes Using Explainable Machine Learning in Children with Asthma.Children (Basel, Switzerland) · 2021Article
- Effect of individual allergen sensitization on omalizumab treatment outcomes in patients with severe allergic asthma determined using data from the Czech Anti-IgE Registry.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2020Article
- FENOMA Study: Achieving Full Control in Patients with Severe Allergic Asthma.Journal of asthma and allergy · 2020Article
- Associated Factors for Asthma Severity in Korean Children: A Korean Childhood Asthma Study.Allergy, asthma & immunology research · 2020Article
- Paraben exposures and asthma-related outcomes among children from the US general population.The Journal of allergy and clinical immunology · 2019Article
- Association of molds and metrological parameters to frequency of severe asthma exacerbation.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019Article
- Sensitization to inhaled allergens in asthmatic children in southern Jordan: a cross-sectional study.Multidisciplinary respiratory medicine · 2019Article
- German Cockroach Extract Induces Matrix Metalloproteinase-1 Expression, Leading to Tight Junction Disruption in Human Airway Epithelial Cells.Yonsei medical journal · 2018Article
- Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.American journal of physiology. Lung cellular and molecular physiology · 2018Article
- Improvement of patient-reported outcomes in severe allergic asthma by omalizumab treatment: the real life observational PROXIMA study.The World Allergy Organization journal · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe asthma is a major health concern. The allergic (IgE-mediated) form of asthma is well known from a pathogenic viewpoint. We searched the available literature to identify which allergens are most frequently associated with severe, refractory or life threatening asthma. According to the results, molds, pet dander, cockroach and ragweed were more frequently responsible for severe asthma. Thunderstorm asthma, in addition, represents a special association between allergic sensitization and an external climatic factor. A detailed knowledge of the most harmful allergens is mandatory for an appropriate diagnostic and preventive approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.