Evidence map›Paper›PMID 28101240›Full record

ArticleOncology letters2016

Downregulation of Annexin A1 is correlated with radioresistance in nasopharyngeal carcinoma.

Lifang Huang, Li Liao, Yanping Wan, Ailan Cheng, Meixiang Li, Sihan Chen, Maoyu Li, Xing Tan, Guqing Zeng

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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  8. [Knockout notch1 gene can enhanced radiosensitivity of nasopharyngeal carcinoma cells].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lifang HuangInstitute of Nursing Research, School of Nursing, University of South China, Hengyang, Hunan 421001, P.R. China.
Li LiaoInstitute of Nursing Research, School of Nursing, University of South China, Hengyang, Hunan 421001, P.R. China.
Yanping WanInstitute of Nursing Research, School of Nursing, University of South China, Hengyang, Hunan 421001, P.R. China.
Ailan ChengCancer Research Institute, School of Medicine, University of South China, Hengyang, Hunan 421001, P.R. China.
Meixiang LiCancer Research Institute, School of Medicine, University of South China, Hengyang, Hunan 421001, P.R. China.
Sihan ChenInstitute of Nursing Research, School of Nursing, University of South China, Hengyang, Hunan 421001, P.R. China.
Maoyu LiKey Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.
Xing TanInstitute of Nursing Research, School of Nursing, University of South China, Hengyang, Hunan 421001, P.R. China.
Guqing ZengInstitute of Nursing Research, School of Nursing, University of South China, Hengyang, Hunan 421001, P.R. China.
University of South China · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiotherapy is the primary treatment for nasopharyngeal carcinoma (NPC), but radioresistance often remains an obstacle to successful treatment. In our previous study, it was demonstrated that Annexin A1 (ANXA1) was involved in the p53-mediated radioresponse in NPC cells, which suggested that it may be associated with radioresistance in NPC; however, the role of ANXA1 in NPC radioresistance is unknown. In the present study, CNE2 cells were stably transfected with pLKO.1-ANXA1-small hairpin (sh)RNAs to investigate the effects of ANXA1 on the radiosensitivity of NPC. CNE2 cells transfected with pLKO.1 were used as the control. The radiosensitivities of the cells

Indexed as

Annexin A1ionizing radiationnasopharyngeal carcinomaradioresistance

Identifiers

PMID28101240
PMCPMC5228272
OpenAlexW2540129567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.