Evidence map›Paper›PMID 28101004›Full record

ReviewFrontiers in cellular neuroscience2016

Cannabinoid Receptors in the Central Nervous System: Their Signaling and Roles in Disease.

Debra A Kendall, Guillermo A Yudowski

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 195 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
195citing papers in PubMed, 5 pooled it
19.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

195 citing papers in PubMed, 5 syntheses or guidelines pooled it, 348 citations in OpenAlex.

  1. Cannabinoids and opioid consumption in cancer pain: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Cannabis-Induced Gastrointestinal Tract Symptoms in the Adult Population: A Systematic Review.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024
    Pooled it
  3. Pooled it
  4. The Autism-Psychosis Continuum Conundrum: Exploring the Role of the Endocannabinoid System.International journal of environmental research and public health · 2022
    Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Review
  9. Side-Chain Homologs of ΔMolecular neurobiology · 2026
    Article
  10. Review
  11. Dynamic mechanism for subtype selectivity of endocannabinoids.The Journal of biological chemistry · 2026
    Article
  12. Review
  13. Selected Cannabinoids, Cannabimimetic Agents andPharmaceuticals (Basel, Switzerland) · 2026
    Review
  14. Review
  15. Article
  16. Overlapping pathways of migraine and the endocannabinoid system: Potential therapeutic targets.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  17. Article
  18. Review
  19. Article
  20. Article

135 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Debra A KendallDepartment of Pharmaceutical Sciences, University of Connecticut Storrs, CT, USA.
Guillermo A YudowskiDepartment of Anatomy and Neurobiology, University of Puerto Rico, Medical Sciences CampusSan Juan, Puerto Rico; Institute of Neurobiology, University of Puerto RicoSan Juan, Puerto Rico.
University of Connecticut · USUniversity of Puerto Rico, Medical Sciences Campus · PR

Funding

Endocytic mechanisms controlling functional selectivity of the CB1RR01DA037924 · NIDA · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI SOSA, MARIA A · 2014 to 2018
$1.7M
Beta-Arrestin Signaling from the Cannabinoid 2 and mu Opioid ReceptorsR21DA040920 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI KENDALL, DEBRA A · 2016 to 2017
$439k
NIDA NIH HHS R01 DA037924NIDA NIH HHS R21 DA040920
6 · The paper itself

Abstract

The identification and cloning of the two major cannabinoid (CB

Indexed as

CB1 receptorsendocannabinoid systemneuromodulationsignalingΔ9-THC

Identifiers

PMID28101004
PMCPMC5209363
OpenAlexW2565813493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.