Evidence map›Paper›PMID 28100791›Full record

ArticleMolecular biology and evolution2017

The Reliability and Stability of an Inferred Phylogenetic Tree from Empirical Data.

Yukako Katsura, Craig E Stanley, Sudhir Kumar, Masatoshi Nei

Abstract read
In one paragraph

Article in Molecular biology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Genome-wide comparison andFrontiers in genetics · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yukako KatsuraDepartment of Biology and Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA.
Craig E StanleyDepartment of Biology and Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA.
Sudhir KumarDepartment of Biology and Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA.
Masatoshi NeiDepartment of Biology and Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA.

Funding

COMPARATIVE MOLECULAR SEQUENCE ANALYSISR01HG002096 · NHGRI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI KUMAR, SUDHIR · 2000 to 2013
$3.0M
NHGRI NIH HHS R01 HG002096
6 · The paper itself

Abstract

The reliability of a phylogenetic tree obtained from empirical data is usually measured by the bootstrap probability (Pb) of interior branches of the tree. If the bootstrap probability is high for most branches, the tree is considered to be reliable. If some interior branches show relatively low bootstrap probabilities, we are not sure that the inferred tree is really reliable. Here, we propose another quantity measuring the reliability of the tree called the stability of a subtree. This quantity refers to the probability of obtaining a subtree (Ps) of an inferred tree obtained. We then show that if the tree is to be reliable, both Pb and Ps must be high. We also show that Ps is given by a bootstrap probability of the subtree with the closest outgroup sequence, and computer program RESTA for computing the Pb and Ps values will be presented.

Indexed as

Models, GeneticPhylogenyAnimalsComputational BiologyComputer SimulationGenes, MHC Class IIHistocompatibility Antigens Class IIMammalsProbabilityReproducibility of ResultsSequence Analysis, DNASoftwareHistocompatibility Antigens Class IIbootstrap probabilitycomputer program RESTA.MHC class II β chain genesphylogenetic treesreliabilitystabilitysubtrees

Identifiers

PMID28100791
PMCPMC5850655

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.